PTPRZ1 and ADD2

Number of citations of the paper that reports this interaction (PMID 16105548)
16

Data Source:
HPRD (in vivo)

		PTPRZ1	ADD2
Gene Name		protein tyrosine phosphatase, receptor-type, Z polypeptide 1	adducin 2 (beta)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Integral Component Of Plasma Membrane Perineuronal Net	Plasma Membrane F-actin Capping Protein Complex Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding	Actin Binding Structural Molecule Activity Calmodulin Binding Spectrin Binding Protein Homodimerization Activity Protein Heterodimerization Activity Actin Filament Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Protein Dephosphorylation Axonogenesis Central Nervous System Development Learning Or Memory Peptidyl-tyrosine Dephosphorylation Oligodendrocyte Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation	Protein Complex Assembly Actin Cytoskeleton Organization Hemopoiesis Positive Regulation Of Protein Binding Barbed-end Actin Filament Capping Actin Filament Bundle Assembly
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: ADD2 ALK ARHGAP35 CTNNB1 FYN GIT1 HMGB1 MDK PTN TNR	8 interactors: ADD1 APP CALM1 FYN PRKACA PRKCD PTPRZ1 RPH3A
Entrez ID		5803	119
HPRD ID		01481	00037
Ensembl ID		ENSG00000106278	ENSG00000075340
Uniprot IDs		B4DFE7 C9JFM0 P23471	P35612 Q05DK5
PDB IDs		3JXF 3S97
Enriched GO Terms of Interacting Partners?		Nervous System Development System Development Neuron Differentiation Multicellular Organismal Development Locomotion Anatomical Structure Development Movement Of Cell Or Subcellular Component Forebrain Development Developmental Process Generation Of Neurons Neuron Development Neurogenesis Cell Development Chemotaxis Learning Or Memory Cognition Cell Morphogenesis Involved In Differentiation Cell Differentiation Brain Development Head Development Neuron Projection Development Cell Migration Axon Guidance Cell Motility Learning Central Nervous System Development Single-organism Behavior Regulation Of Cell Morphogenesis Response To External Stimulus Cell Morphogenesis Regulation Of DNA-templated Transcription, Initiation Organ Development Regulation Of Cellular Component Organization Axonogenesis Cell Projection Organization Axon Development Negative Regulation Of Neuron Death Cell Morphogenesis Involved In Neuron Differentiation Behavior Neuron Projection Morphogenesis Regulation Of Neurogenesis Regulation Of Cell Division Regulation Of Apoptotic Process Regulation Of Neuron Death Telencephalon Development Regulation Of Cell Death Cell Projection Morphogenesis Regulation Of Cell Development Cell Part Morphogenesis Cellular Component Disassembly Involved In Execution Phase Of Apoptosis	Platelet Activation Vascular Endothelial Growth Factor Receptor Signaling Pathway Blood Coagulation Regulation Of Protein Binding Hemostasis Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Immune System Process Neurotrophin TRK Receptor Signaling Pathway Regulation Of Body Fluid Levels Activation Of Phospholipase C Activity Neurotrophin Signaling Pathway Wound Healing Positive Regulation Of Phospholipase C Activity Regulation Of Binding Cell Activation Response To Wounding Regulation Of Protein Kinase Activity Positive Regulation Of Phospholipase Activity Regulation Of Kinase Activity Innate Immune Response Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Negative Regulation Of Glial Cell Apoptotic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Hydrolase Activity Regulation Of Protein Phosphorylation Regulation Of Platelet Aggregation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Ketone Metabolic Process Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Protein Metabolic Process Detection Of Abiotic Stimulus Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Dephosphorylation Cellular Response To Growth Factor Stimulus Immune Response Regulation Of Phosphorylation Response To Growth Factor Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Defense Response Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Regulation Of Peptidyl-tyrosine Phosphorylation
Tagcloud ?		alters annotation ca3 candidate cdh23 dataset disequilibrium ear fdr filtering gwas harbored hist3h3 hypotheses hypothetical icsnpathway il27ra innate modulates morphogenesis pneumoconiosis rs11592462 rs2230656 rs2292151 rs8120 snps stereocilia strongest ticam1	2p13 4p16 acceptor adducin alternative alternatively codons comprises conform consensus duplication ets exon exons frame gata intron isoform mapping mzf1 overlapping smallest sp1 spans splice spliced stop termination utr
Tagcloud (Difference) ?		alters annotation ca3 candidate cdh23 dataset disequilibrium ear fdr filtering gwas harbored hist3h3 hypotheses hypothetical icsnpathway il27ra innate modulates morphogenesis pneumoconiosis rs11592462 rs2230656 rs2292151 rs8120 snps stereocilia strongest ticam1	2p13 4p16 acceptor adducin alternative alternatively codons comprises conform consensus duplication ets exon exons frame gata intron isoform mapping mzf1 overlapping smallest sp1 spans splice spliced stop termination utr
Tagcloud (Intersection) ?