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RNF11 and UBE2D4
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
BioGRID
(two hybrid, two hybrid)
HPRD
(two hybrid)
RNF11
UBE2D4
Gene Name
ring finger protein 11
ubiquitin-conjugating enzyme E2D 4 (putative)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Early Endosome
Recycling Endosome
Extracellular Vesicular Exosome
Molecular Function
DNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein Autoubiquitination
Protein Ubiquitination
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Ventricular conduction (
21076409
)
Protein-Protein Interactions
68 interactors:
AKT1
ANKRD13A
APP
ASCC2
AUP1
CALCOCO2
CBLB
CCDC127
DCUN1D1
EPN1
EPN2
EPN3
EPS15
ERCC6
GGA1
GGA2
GGA3
HERC1
HERC2
HUWE1
IKBKG
ITCH
MYO6
NEDD4
NEDD4L
OPTN
PDCD6IP
POLI
PTPRC
QARS
RABGEF1
RIPK1
RNF168
RNF216
RPS27A
SDCBP
SMURF1
SMURF2
SNRNP70
SPRTN
STAM2
STAMBP
STAMBPL1
TAX1BP1
TNFAIP3
TNIP1
TOM1L2
UBA52
UBAC1
UBB
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2N
UBE2U
UBQLN2
UBQLN4
USP5
WWP1
WWP2
ZFYVE16
ZFYVE9
ZNF350
90 interactors:
AMFR
ARIH2
BFAR
BIRC8
CADPS2
CHFR
CNOT4
DAZAP2
DTX1
DTX2
DTX3
DTX3L
DZIP3
INCA1
LRSAM1
MAGEA11
MAP3K1
MARCH3
MGRN1
MIB1
MID1
MID2
MKRN2
MKRN3
MUL1
MYBL2
MYLIP
OTUB1
PHF7
PJA2
RBCK1
RCHY1
RFWD3
RING1
RLIM
RMND5B
RNF10
RNF103
RNF11
RNF111
RNF114
RNF115
RNF125
RNF126
RNF13
RNF130
RNF138
RNF14
RNF150
RNF165
RNF166
RNF167
RNF181
RNF185
RNF2
RNF25
RNF26
RNF38
RNF4
RNF43
RNF5
RNF7
SIAH1
TOPORS
TRAF6
TRAF7
TRIM10
TRIM17
TRIM2
TRIM25
TRIM27
TRIM3
TRIM31
TRIM35
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM8
UBE4A
UBOX5
UBTD1
UFM1
UHRF2
XIAP
ZNRF1
ZNRF2
ZNRF4
Entrez ID
26994
51619
HPRD ID
09955
14242
Ensembl ID
ENSG00000123091
ENSG00000078967
Uniprot IDs
Q9Y3C5
Q9Y2X8
PDB IDs
Enriched GO Terms of Interacting Partners
?
Protein Ubiquitination
Protein Polyubiquitination
Protein Modification By Small Protein Conjugation
Protein Catabolic Process
Cellular Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Cellular Macromolecule Catabolic Process
Positive Regulation Of Protein Catabolic Process
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Proteolysis
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Positive Regulation Of Innate Immune Response
Regulation Of Protein Catabolic Process
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Cellular Protein Modification Process
Regulation Of Type I Interferon Production
Toll-like Receptor Signaling Pathway
Negative Regulation Of Signaling
Toll-like Receptor 4 Signaling Pathway
Protein K63-linked Ubiquitination
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Innate Immune Response
TRIF-dependent Toll-like Receptor Signaling Pathway
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Catabolic Process
Cellular Protein Metabolic Process
Proteasomal Protein Catabolic Process
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Type I Interferon Production
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Immune Response-regulating Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Intracellular Transport
Cellular Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Transforming Growth Factor Beta Receptor Signaling Pathway
Protein Metabolic Process
Intracellular Protein Transport
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Innate Immune Response
Cellular Response To Stimulus
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Protein Polyubiquitination
Protein Autoubiquitination
Cellular Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein K63-linked Ubiquitination
Regulation Of Viral Entry Into Host Cell
Protein K48-linked Ubiquitination
Regulation Of Viral Release From Host Cell
Negative Regulation Of Viral Release From Host Cell
Negative Regulation Of Viral Entry Into Host Cell
Metabolic Process
Negative Regulation Of Viral Process
Catabolic Process
Proteolysis
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Viral Process
Protein Monoubiquitination
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Signal Transduction
Negative Regulation Of Viral Transcription
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Process
Regulation Of Signal Transduction
Innate Immune Response
Interferon-gamma-mediated Signaling Pathway
Regulation Of Protein Ubiquitination
Cellular Response To Interferon-gamma
Regulation Of Signaling
Positive Regulation Of Intracellular Signal Transduction
Apoptotic Process
Response To Interferon-gamma
Programmed Cell Death
Cell Death
Death
Histone Monoubiquitination
Tagcloud
?
accumulation
apoptosis
apoptotic
arsenic
cadmium
conjugating
degradation
downregulation
elevated
enzymes
family
hand
induce
inorganic
mercury
p53
promote
proteasomal
proximal
rat
suppressed
suppression
tubular
ubiquitin
ubiquitination
Tagcloud (Difference)
?
accumulation
apoptosis
apoptotic
arsenic
cadmium
conjugating
degradation
downregulation
elevated
enzymes
family
hand
induce
inorganic
mercury
p53
promote
proteasomal
proximal
rat
suppressed
suppression
tubular
ubiquitin
ubiquitination
Tagcloud (Intersection)
?