RNF11 and GGA1

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		RNF11	GGA1
Gene Name		ring finger protein 11	golgi-associated, gamma adaptin ear containing, ARF binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Early Endosome Recycling Endosome Extracellular Vesicular Exosome	Nucleoplasm Golgi Apparatus Endosome Membrane Membrane Clathrin Adaptor Complex Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding	Molecular_function Protein Binding
	Biological Process	Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination	Intracellular Protein Transport Vesicle-mediated Transport Positive Regulation Of Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Ventricular conduction ( 21076409)
Protein-Protein Interactions		68 interactors: AKT1 ANKRD13A APP ASCC2 AUP1 CALCOCO2 CBLB CCDC127 DCUN1D1 EPN1 EPN2 EPN3 EPS15 ERCC6 GGA1 GGA2 GGA3 HERC1 HERC2 HUWE1 IKBKG ITCH MYO6 NEDD4 NEDD4L OPTN PDCD6IP POLI PTPRC QARS RABGEF1 RIPK1 RNF168 RNF216 RPS27A SDCBP SMURF1 SMURF2 SNRNP70 SPRTN STAM2 STAMBP STAMBPL1 TAX1BP1 TNFAIP3 TNIP1 TOM1L2 UBA52 UBAC1 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN2 UBQLN4 USP5 WWP1 WWP2 ZFYVE16 ZFYVE9 ZNF350	36 interactors: AFTPH AP1AR APP ARF1 ARF3 ARF5 ARF6 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CLINT1 CLTC CSNK2A1 DTNB F8 GGA2 GGA3 IGF2R LRP3 M6PR RAB5A RABEP1 RABGEF1 RNF11 RPS27A SMAD3 SORL1 SORT1 STAB1 SYNRG TSG101 UBC VPS18
Entrez ID		26994	26088
HPRD ID		09955	12078
Ensembl ID		ENSG00000123091	ENSG00000100083
Uniprot IDs		Q9Y3C5	Q6IC75 Q9UJY5
PDB IDs			1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Cellular Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Cellular Macromolecule Catabolic Process Positive Regulation Of Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Proteolysis Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of Innate Immune Response Regulation Of Protein Catabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Protein Modification Process Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Negative Regulation Of Signaling Toll-like Receptor 4 Signaling Pathway Protein K63-linked Ubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Protein Metabolic Process Proteasomal Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Protein Metabolic Process Negative Regulation Of Type I Interferon Production Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Immune Response-regulating Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Intracellular Transport Cellular Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Transforming Growth Factor Beta Receptor Signaling Pathway Protein Metabolic Process Intracellular Protein Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Innate Immune Response Cellular Response To Stimulus	Vesicle-mediated Transport Transport Protein Transport Establishment Of Protein Localization Endocytosis Intracellular Transport Protein Localization Establishment Of Localization In Cell Cellular Localization Post-Golgi Vesicle-mediated Transport Endosomal Transport Viral Protein Processing Receptor-mediated Endocytosis Regulation Of Vesicle-mediated Transport Protein Processing Regulation Of Cellular Component Organization Cellular Protein Localization Golgi Vesicle Transport Negative Regulation Of Protein Metabolic Process Intracellular Protein Transport Virion Assembly Apoptotic Process Programmed Cell Death Intracellular Transport Of Virus Cell Death Death Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Protein Catabolic Process Regulation Of Cell Cycle Phase Transition Membrane Organization Regulation Of Mitotic Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Proteolysis Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Lysosomal Transport Positive Regulation Of Proteolysis Positive Regulation Of Wnt Signaling Pathway Regulation Of Cellular Localization Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Viral Process Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Growth Regulation Of Endocytosis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Viral Life Cycle Positive Regulation Of Cell Cycle Arrest
Tagcloud ?			adpkd arl3 autosomal cilia ciliary ciliopathies cleaved couples golgi gps localize milieu module must pc1 pc2 polycystic polycystin proper proteolytically rabep1 reach sense tgn traffic trafficking transmembrane tubular whereby
Tagcloud (Difference) ?			adpkd arl3 autosomal cilia ciliary ciliopathies cleaved couples golgi gps localize milieu module must pc1 pc2 polycystic polycystin proper proteolytically rabep1 reach sense tgn traffic trafficking transmembrane tubular whereby
Tagcloud (Intersection) ?