RNF11 and TNIP1

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		RNF11	TNIP1
Gene Name		ring finger protein 11	TNFAIP3 interacting protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Early Endosome Recycling Endosome Extracellular Vesicular Exosome	Intracellular Nucleus Cytoplasm
	Molecular Function	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding	Ubiquitin-specific Protease Activity Protein Binding Mitogen-activated Protein Kinase Binding
	Biological Process	Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination	MyD88-dependent Toll-like Receptor Signaling Pathway Translation Defense Response Inflammatory Response Leukocyte Cell-cell Adhesion Glycoprotein Biosynthetic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Inflammatory Response Negative Regulation Of ERK1 And ERK2 Cascade Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade
Pathways
Drugs
Diseases
GWAS		Ventricular conduction ( 21076409)	Inflammatory bowel disease ( 23128233) Myasthenia gravis ( 23055271) Psoriasis ( 19169254) Systemic lupus erythematosus ( 23273568 19838193) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic sclerosis ( 21750679)
Protein-Protein Interactions		68 interactors: AKT1 ANKRD13A APP ASCC2 AUP1 CALCOCO2 CBLB CCDC127 DCUN1D1 EPN1 EPN2 EPN3 EPS15 ERCC6 GGA1 GGA2 GGA3 HERC1 HERC2 HUWE1 IKBKG ITCH MYO6 NEDD4 NEDD4L OPTN PDCD6IP POLI PTPRC QARS RABGEF1 RIPK1 RNF168 RNF216 RPS27A SDCBP SMURF1 SMURF2 SNRNP70 SPRTN STAM2 STAMBP STAMBPL1 TAX1BP1 TNFAIP3 TNIP1 TOM1L2 UBA52 UBAC1 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN2 UBQLN4 USP5 WWP1 WWP2 ZFYVE16 ZFYVE9 ZNF350	61 interactors: ADH6 AP1M1 BYSL CCDC112 CCNG1 CDIP1 CDKN1A CFAP53 EFEMP1 EHHADH FAM161A FAM168A FUS GABARAPL1 GABARAPL2 GIT2 GTF2B GTF2H1 HDDC3 IKBKG KIFC3 MAGEB18 MAGEH1 MAP1LC3A MAP1LC3B MAPK1 MAPK10 MOB1B MOB3C MORF4L1 MORF4L2 NDC80 NFKB1 NIFK NME7 OPTN PIN1 PNKP RABAC1 RALBP1 RARA RARG RBFOX1 RNF11 RPL5 S100B SELPLG SNIP1 SUMO2 SYT6 TAX1BP1 TCEA2 TCEANC2 TNFAIP3 TNIP3 TTF2 TXLNA UBC VPS33B ZBTB25 ZNHIT1
Entrez ID		26994	10318
HPRD ID		09955	09216
Ensembl ID		ENSG00000123091	ENSG00000145901
Uniprot IDs		Q9Y3C5	A4F1W8 A4F1W9 A4F1X2 A8K4N4 B7Z8K2 E7EPY1 E7ET96 Q05KP3 Q05KP4 Q15025
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Cellular Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Cellular Macromolecule Catabolic Process Positive Regulation Of Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Proteolysis Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of Innate Immune Response Regulation Of Protein Catabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Protein Modification Process Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Negative Regulation Of Signaling Toll-like Receptor 4 Signaling Pathway Protein K63-linked Ubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Protein Metabolic Process Proteasomal Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Protein Metabolic Process Negative Regulation Of Type I Interferon Production Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Immune Response-regulating Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Intracellular Transport Cellular Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Transforming Growth Factor Beta Receptor Signaling Pathway Protein Metabolic Process Intracellular Protein Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Innate Immune Response Cellular Response To Stimulus	Cellular Response To Stress MyD88-independent Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Toll-like Receptor 4 Signaling Pathway Activation Of Innate Immune Response Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Stress Nucleophagy Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Macroautophagy Positive Regulation Of Innate Immune Response Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Mitochondrion Degradation MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Innate Immune Response Organelle Disassembly Autophagic Vacuole Assembly Negative Regulation Of Type I Interferon Production Negative Regulation Of Cytokine Production Cellular Response To Nitrogen Starvation Cellular Response To Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Extracellular Stimulus I-kappaB Kinase/NF-kappaB Signaling Immune Response-regulating Signaling Pathway Membrane Fusion Innate Immune Response Fc-epsilon Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling RNA Metabolic Process Cellular Response To Starvation Cellular Response To DNA Damage Stimulus Membrane Organization Cellular Response To Lipopolysaccharide Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Molecule Of Bacterial Origin Autophagy Response To Stimulus Fc Receptor Signaling Pathway Defense Response Transcription Initiation From RNA Polymerase II Promoter Response To External Stimulus
Tagcloud ?			1q21 5q31 6p21 alleles anxa6 applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic prkra psoriasis rarely shared th2 traits unreported utilizing
Tagcloud (Difference) ?			1q21 5q31 6p21 alleles anxa6 applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic prkra psoriasis rarely shared th2 traits unreported utilizing
Tagcloud (Intersection) ?