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RNF11 and UBQLN2
Number of citations of the paper that reports this interaction (PubMedID
15231748
)
54
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
RNF11
UBQLN2
Description
ring finger protein 11
ubiquilin 2
Image
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Cytoplasm
Endosome
Early Endosome
Recycling Endosome
Extracellular Exosome
Nucleus
Cytoplasm
Autophagosome
Cytosol
Plasma Membrane
Membrane
Cytoplasmic Vesicle
Molecular Function
DNA Binding
Protein Binding
Zinc Ion Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Protein Binding
Polyubiquitin Modification-dependent Protein Binding
Identical Protein Binding
Molecular Condensate Scaffold Activity
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Protein Autoubiquitination
Autophagosome Assembly
Ubiquitin-dependent Protein Catabolic Process
Autophagy
Regulation Of Macroautophagy
ERAD Pathway
Negative Regulation Of Transport
Negative Regulation Of Clathrin-dependent Endocytosis
Negative Regulation Of G Protein-coupled Receptor Internalization
Positive Regulation Of ERAD Pathway
Regulation Of Autophagosome Assembly
Pathways
Cargo recognition for clathrin-mediated endocytosis
Drugs
Diseases
GWAS
Atrial fibrillation (
29290336
)
Male-pattern baldness (
28196072
)
QRS duration (
21076409
)
Interacting Genes
69 interacting genes:
AKT1
ANKRD13A
ANKRD28
APP
ASCC2
AUP1
CALCOCO2
CBLB
CCDC127
DCUN1D1
EPN1
EPN2
EPN3
EPS15
ERCC6
FANCL
GGA1
GGA2
GGA3
HERC1
HERC2
HUWE1
IKBKG
ITCH
MYO6
NEDD4
NEDD4L
OPTN
PDCD6IP
POLI
PTPRC
QARS1
RABGEF1
RIPK1
RNF168
RNF216
RPS27A
SDCBP
SMURF1
SMURF2
SNRNP70
SPRTN
STAM2
STAMBP
TAX1BP1
TNFAIP3
TNIP1
TOM1L2
UBA52
UBAC1
UBB
UBC
UBE2D1
UBE2D2
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2N
UBE2U
UBQLN2
UBQLN4
USP5
WWP1
WWP2
YAP1
ZFYVE16
ZFYVE9
ZNF350
246 interacting genes:
-
ABI2
ACOT7
ADAMTS3
ADRM1
AGR2
AGR3
AMBN
ANKRD33
APOC2
APOC4
ARRDC3
ASCL1
ATP6V1G1
ATXN7
AZGP1
BAG6
BPIFA1
BTRC
C1orf94
C1QA
C1QB
C1QC
C1QL4
C1QTNF2
C1QTNF4
C6orf15
C8G
CCDC158
CCK
CCL16
CCL3
CCL7
CCN1
CD93
CD99L2
CDH15
CDH17
CDIP1
CDSN
CEACAM6
CLEC11A
CLPSL2
CNNM3
COL10A1
COL17A1
COL1A2
COL8A1
COL9A2
COLGALT2
CSN1S1
CSN2
CSN3
CST1
CST4
CTAG1A
CTAG1B
CTDNEP1
DAZAP2
DDR1
DEFA1
DEFA1B
DEFA6
DEFB115
DMKN
DUSP21
ECM1
ECRG4
EFEMP1
EGFL6
ERP27
ERP29
ETNK1
F10
FAM168A
FAM222B
FBXO25
FDCSP
FGF17
FKBP2
FNDC11
FUCA1
FUS
FZD7
GAL
GALP
GHRL
GPR162
GPX7
GUCA2A
GUCA2B
HEMK1
HERC3
HERPUD1
HNRNPA3
HSD17B12
HSPA13
HSPA1B
ICAM1
IFNA13
IGFBP6
IGLL1
IL11
IQCF3
IST1
ITPKB
ITPRIPL1
JPH4
KISS1
KLHL11
KLHL42
KRT6A
KRTAP12-1
KRTAP13-1
KRTAP19-3
KRTAP19-5
LAIR2
LCN1
LCN2
LITAF
LMO4
LY6G6D
MBL2
MDK
MICOS10-NBL1
MIEF1
MIEF2
MINPP1
MOAP1
MTNR1B
MTX2
MYDGF
MYO15B
NAXD
NBL1
NDOR1
NME3
NOC4L
NOL3
NPBWR1
NPPA
NPVF
NPY
NRN1L
NT5C3A
NUP58
ODAPH
OPN4
OR7D4
OSMR
PARM1
PCDHGA9
PIANP
PIK3IP1
PIN1
PLAAT2
PLAAT3
PLEKHB2
PMEPA1
PNMA3
PODXL
POLE2
POM121
PPIB
PPIC
PPIH
PRAP1
PRPF40A
PRR4
PSMD4
PSORS1C2
PTGDS
QPCT
RASSF5
RBFOX2
RBM24
RNF11
RNF128
RNF208
RNF4
RPN1
RSRC2
RTL8A
RTL8B
RTL8C
SCG5
SCGB2B2
SEMG1
SERPINE1
SERPINI2
SEZ6
SEZ6L
SFTPA2
SGTA
SLC16A3
SLC29A2
SLITRK1
SLPI
SMIM11
SMIM19
SMIM2
SMR3B
SMURF1
SNRPB
SOD3
SPAG11B
SPINT1
SPN
SRGN
SRP68
SUOX
SUSD4
TBK1
TENT5B
TFF3
TIMM21
TIMM44
TIMP2
TMEM123
TNFRSF18
TOMM20L
TXNDC12
TXNDC5
UACA
UBA52
UBAC1
UBB
UBC
UBE2I
UBE2V1
UBE3A
UBQLN4
UBXN1
UBXN7
UFSP1
VENTX
VIP
VTN
VWC2
WFDC10B
WFDC12
ZFAND2A
ZFAND2B
ZG16
ZG16B
ZNF205
Entrez ID
26994
29978
HPRD ID
09955
02224
Ensembl ID
ENSG00000123091
ENSG00000188021
Uniprot IDs
Q9Y3C5
Q9UHD9
PDB IDs
1J8C
2NBV
6MUN
7F7X
Enriched GO Terms of Interacting Partners
?
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Post-translational Protein Modification
Ubiquitin-protein Transferase Activity
Protein Metabolic Process
Proteolysis Involved In Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Modification Process
Macromolecule Catabolic Process
Protein Polyubiquitination
Proteolysis
Ubiquitin Binding
Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Positive Regulation Of Protein Metabolic Process
Ubiquitin Protein Ligase Activity
Cytosol
Macromolecule Metabolic Process
Protein Catabolic Process
Ubiquitin Conjugating Enzyme Activity
Protein Monoubiquitination
Endosome
Ubiquitin Ligase Complex
Proteasomal Protein Catabolic Process
Polyubiquitin Modification-dependent Protein Binding
Regulation Of Protein Catabolic Process
Regulation Of Protein Metabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Nucleoplasm
Negative Regulation Of Signal Transduction
Positive Regulation Of Catabolic Process
Protein K63-linked Ubiquitination
Positive Regulation Of Protein Catabolic Process
K63-linked Polyubiquitin Modification-dependent Protein Binding
Transferase Activity
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Post-translational Protein Modification
Negative Regulation Of Canonical NF-kappaB Signal Transduction
Early Endosome Membrane
Positive Regulation Of Protein Modification Process
Autophagosome
Protein-containing Complex
Positive Regulation Of Post-translational Protein Modification
DNA Damage Response
Regulation Of Protein Ubiquitination
Cytoplasm
Cellular Response To Stress
Extracellular Exosome
Extracellular Region
Extracellular Space
Protein Binding
Humoral Immune Response
Collagen Trimer
Antimicrobial Humoral Response
Defense Response To Bacterium
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Antibacterial Humoral Response
Extracellular Matrix
Endoplasmic Reticulum Lumen
Response To Bacterium
Complement Component C1q Complex
Protein Targeting To ER
Neuropeptide Hormone Activity
Establishment Of Protein Localization To Endoplasmic Reticulum
Modification-dependent Protein Catabolic Process
Complement Activation, Classical Pathway
Regulation Of Proteolysis
Positive Regulation Of Cell-substrate Adhesion
Polyubiquitin Modification-dependent Protein Binding
Regulation Of Cell-substrate Adhesion
IgM Binding
Complement Component C1 Complex
Disruption Of Plasma Membrane Integrity In Another Organism
Guanylate Cyclase Activator Activity
Defense Response To Symbiont
Peptidase Inhibitor Activity
Defense Response To Other Organism
Defense Response To Gram-negative Bacterium
Defense Response To Gram-positive Bacterium
Proteolysis Involved In Protein Catabolic Process
Pore-forming Activity
Complement Activation
Neuropeptide Signaling Pathway
Regulation Of Behavior
Establishment Of Protein Localization To Organelle
Symbiont Cell Surface
Peptidyl-prolyl Cis-trans Isomerase Activity
Extrinsic Component Of Postsynaptic Membrane
Ubiquitin-dependent Protein Catabolic Process
Smooth Muscle Cell-matrix Adhesion
Cytoplasmic Side Of Late Endosome Membrane
Extracellular Matrix Structural Constituent Conferring Tensile Strength
Hormone Activity
Cyclosporin A Binding
Regulation Of Mononuclear Cell Migration
Synapse Pruning
K48-linked Polyubiquitin Modification-dependent Protein Binding
Regulation Of Response To Endoplasmic Reticulum Stress
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Tagcloud (Intersection)
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