PTPN9 and GET1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PTPN9	GET1
Description		protein tyrosine phosphatase non-receptor type 9	guided entry of tail-anchored proteins factor 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Neuron Projection Terminus	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity	Protein Binding Protein-membrane Adaptor Activity
	Biological Process	Protein Dephosphorylation Signal Transduction Negative Regulation Of Neuron Projection Development Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Protein Localization To Plasma Membrane	Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Sensory Perception Of Sound Protein Insertion Into ER Membrane Synapse Organization Protein Stabilization Establishment Of Localization In Cell Otic Vesicle Development Tail-anchored Membrane Protein Insertion Into ER Membrane Establishment Of Protein Localization To Membrane
Pathways		Interleukin-37 signaling	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Height ( 20189936 25429064 31562340 33713608) Hip circumference adjusted for BMI ( 34021172) Type 2 diabetes ( 30297969)
Interacting Genes		46 interacting genes: AGTRAP AQP6 ARL13B ARL6IP1 ATP5PF BSND CCR2 CDR1 CERS4 CMTM4 CMTM5 COQ3 CPLX4 CREB3 CREB3L1 DERL2 EBP FAM114A2 FKBP7 GET1 GHR GJB1 GORAB HSD17B11 HSD17B13 LIME1 LMNA MAL2 NSF PBX3 PEX12 PLIN3 REEP6 RTN3 SCAMP1 SLC16A13 SLC30A8 SLC7A1 SPAG4 STX6 SYP TMCO2 TMEM80 TMEM86B TMX2 YIF1A	28 interacting genes: ABHD5 APOA2 APOL2 AQP1 CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 HMOX2 HTATIP2 ORMDL3 PLPP4 PTPN9 RASGRP3 RTP2 SERP2 SLC35E3 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42
Entrez ID		5780	7485
HPRD ID		02864	04224
Ensembl ID		ENSG00000169410	ENSG00000182093
Uniprot IDs		P43378 Q6IQ43	O00258
PDB IDs		2PA5 4GE2 4GE5 4GE6 4ICZ 6KZQ 6L03	6SO5 8CQZ 8CR1 8CR2
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Steroid Dehydrogenase Activity Endoplasmic Reticulum Tubular Network Formation Protein Binding Endoplasmic Reticulum Tubular Network Membrane Organization Syntaxin Binding Non-motile Cilium Assembly	Basolateral Plasma Membrane Membrane Serine Palmitoyltransferase Complex
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