PTPN9 and NSF

Number of citations of the paper that reports this interaction (PMID 15322554)
26

Data Source:
HPRD (in vitro)

		PTPN9	NSF
Gene Name		protein tyrosine phosphatase, non-receptor type 9	N-ethylmaleimide-sensitive factor
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Cytoplasm Lysosomal Membrane Golgi Stack Cytosol Plasma Membrane Postsynaptic Density Dendritic Shaft Extracellular Vesicular Exosome
	Molecular Function	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding	Protein Binding ATP Binding ATPase Activity Syntaxin-1 Binding Rab GTPase Binding Protein Kinase Binding PDZ Domain Binding Protein Complex Binding ATPase Activity, Coupled Metal Ion Binding
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation	Positive Regulation Of Receptor Recycling Potassium Ion Transport Exocytosis Intra-Golgi Vesicle-mediated Transport Synaptic Transmission Vesicle-mediated Transport Regulation Of Exocytosis Golgi To Plasma Membrane Protein Transport Plasma Membrane Fusion Golgi Vesicle Docking
Pathways			Trafficking of GluR2-containing AMPA receptors Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Trafficking of AMPA receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Height ( 20189936)	Parkinson's disease ( 19915575 21812969)
Protein-Protein Interactions		8 interactors: AGTRAP CMTM5 GHR MAL2 NSF REEP6 RTN3 STX6	25 interactors: ARRB1 C14orf1 CD28 DRD2 EIF3E FUNDC2 GABARAP GABARAPL2 GABBR1 GABBR2 GOSR1 GRIA2 GRIA3 KIAA1377 LUC7L2 NAPA NAPG PTPN9 RAMP3 RPLP1 STX1A STX4 STX8 USO1 VAPA
Entrez ID		5780	4905
HPRD ID		02864	03380
Ensembl ID		ENSG00000169410	ENSG00000073969
Uniprot IDs		P43378	P46459
PDB IDs		2PA5 4GE2 4GE5 4GE6
Enriched GO Terms of Interacting Partners?		Endomembrane System Organization Vesicle-mediated Transport Golgi Vesicle Docking Membrane Fusion Activation Of JAK2 Kinase Activity Creatinine Metabolic Process Isoleucine Metabolic Process Golgi Ribbon Formation Allantoin Metabolic Process Taurine Metabolic Process Activation Of Janus Kinase Activity Angiotensin-activated Signaling Pathway Endoplasmic Reticulum Tubular Network Organization Golgi Vesicle Transport Valine Metabolic Process Creatine Metabolic Process Response To Cycloheximide Succinate Metabolic Process 2-oxoglutarate Metabolic Process Oxaloacetate Metabolic Process Positive Regulation Of Receptor Recycling Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Plasma Membrane Fusion Insulin-like Growth Factor Receptor Signaling Pathway	Membrane Fusion Membrane Organization Intracellular Transport Golgi Vesicle Transport Protein Localization Establishment Of Localization In Cell Protein Transport Synaptic Transmission Vesicle-mediated Transport Establishment Of Protein Localization Cellular Localization Cell-cell Signaling Intracellular Protein Transport Vesicle Fusion Intra-Golgi Vesicle-mediated Transport Cellular Protein Localization Neuron-neuron Synaptic Transmission Organelle Fusion Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Vesicle Organization Negative Regulation Of CAMP Biosynthetic Process Transport Mitochondrion Degradation Negative Regulation Of CAMP Metabolic Process Negative Regulation Of Nucleotide Metabolic Process Organelle Disassembly Synaptic Transmission, Glutamatergic Receptor Internalization Regulation Of Synaptic Vesicle Priming Regulation Of Protein Localization To Plasma Membrane Regulation Of Adenylate Cyclase Activity Regulation Of Vesicle-mediated Transport Regulation Of Cyclase Activity Regulation Of Insulin Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Cytoplasmic Transport Regulation Of Cellular Localization G-protein Coupled Receptor Internalization Regulation Of Peptide Hormone Secretion Cellular Component Assembly Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Receptor Metabolic Process Vesicle Docking Post-Golgi Vesicle-mediated Transport Regulation Of CAMP Biosynthetic Process Membrane Docking Regulation Of Protein Localization Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway
Tagcloud ?		autophosphorylation called coimmunopricipitated couple da ecs fundamental indentified jak jak1 janus kinases lastly meg2 mutant nonreceptor phosphatases preferentially ptps searched substrate substrates trapping tyk2 tyr1175 tyrosine vegf vegfr2	acetate alkylating amount apical associate attachment bound caco cellubrevin coimmunoprecipitation colocalizes connection define docking epithelium ethylmaleimide munc myristate phorbol predominantly quantity sec1 snap snare snares syntaxin thought verified vesicles
Tagcloud (Difference) ?		autophosphorylation called coimmunopricipitated couple da ecs fundamental indentified jak jak1 janus kinases lastly meg2 mutant nonreceptor phosphatases preferentially ptps searched substrate substrates trapping tyk2 tyr1175 tyrosine vegf vegfr2	acetate alkylating amount apical associate attachment bound caco cellubrevin coimmunoprecipitation colocalizes connection define docking epithelium ethylmaleimide munc myristate phorbol predominantly quantity sec1 snap snare snares syntaxin thought verified vesicles
Tagcloud (Intersection) ?