PTPN9 and MAL2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PTPN9	MAL2
Gene Name		protein tyrosine phosphatase, non-receptor type 9	mal, T-cell differentiation protein 2 (gene/pseudogene)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding	Protein Binding
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS		Height ( 20189936)	Hippocampal atrophy ( 19668339)
Protein-Protein Interactions		8 interactors: AGTRAP CMTM5 GHR MAL2 NSF REEP6 RTN3 STX6	15 interactors: ABCG8 ARFIP2 FAM3A GAD2 PBX3 PPP1CA PTPN9 RAB37 SH3GL1 TBRG4 TPD52 TPD52L1 TPD52L2 TUBB VARS2
Entrez ID		5780	114569
HPRD ID		02864	14351
Ensembl ID		ENSG00000169410	ENSG00000147676
Uniprot IDs		P43378	Q969L2
PDB IDs		2PA5 4GE2 4GE5 4GE6
Enriched GO Terms of Interacting Partners?		Endomembrane System Organization Vesicle-mediated Transport Golgi Vesicle Docking Membrane Fusion Activation Of JAK2 Kinase Activity Creatinine Metabolic Process Isoleucine Metabolic Process Golgi Ribbon Formation Allantoin Metabolic Process Taurine Metabolic Process Activation Of Janus Kinase Activity Angiotensin-activated Signaling Pathway Endoplasmic Reticulum Tubular Network Organization Golgi Vesicle Transport Valine Metabolic Process Creatine Metabolic Process Response To Cycloheximide Succinate Metabolic Process 2-oxoglutarate Metabolic Process Oxaloacetate Metabolic Process Positive Regulation Of Receptor Recycling Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Plasma Membrane Fusion Insulin-like Growth Factor Receptor Signaling Pathway
Tagcloud ?		autophosphorylation called coimmunopricipitated couple da ecs fundamental indentified jak jak1 janus kinases lastly meg2 mutant nonreceptor phosphatases preferentially ptps searched substrate substrates trapping tyk2 tyr1175 tyrosine vegf vegfr2	cease chief he4 imchief immortomice immortomouse imspem lineages metaplasia metaplasias metaplastic myelin nonpermissive owing oxyntic pepsinogen permissive preneoplastic proliferate rab3d reliance resemble secrete sole spasmolytic spem stomach tff2 transdifferentiation
Tagcloud (Difference) ?		autophosphorylation called coimmunopricipitated couple da ecs fundamental indentified jak jak1 janus kinases lastly meg2 mutant nonreceptor phosphatases preferentially ptps searched substrate substrates trapping tyk2 tyr1175 tyrosine vegf vegfr2	cease chief he4 imchief immortomice immortomouse imspem lineages metaplasia metaplasias metaplastic myelin nonpermissive owing oxyntic pepsinogen permissive preneoplastic proliferate rab3d reliance resemble secrete sole spasmolytic spem stomach tff2 transdifferentiation
Tagcloud (Intersection) ?