PTPN9 and FKBP7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PTPN9	FKBP7
Description		protein tyrosine phosphatase non-receptor type 9	FKBP prolyl isomerase 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Neuron Projection Terminus	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding Protein Binding FK506 Binding Isomerase Activity Metal Ion Binding
	Biological Process	Protein Dephosphorylation Signal Transduction Negative Regulation Of Neuron Projection Development Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		Interleukin-37 signaling
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Height ( 20189936 25429064 31562340 33713608) Hip circumference adjusted for BMI ( 34021172) Type 2 diabetes ( 30297969)	Alanine aminotransferase levels ( 33547301) Appendicular lean mass ( 33097823) Aspartate aminotransferase levels ( 33547301) Atrial fibrillation ( 30061737) Blood protein levels ( 30072576) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)
Interacting Genes		46 interacting genes: AGTRAP AQP6 ARL13B ARL6IP1 ATP5PF BSND CCR2 CDR1 CERS4 CMTM4 CMTM5 COQ3 CPLX4 CREB3 CREB3L1 DERL2 EBP FAM114A2 FKBP7 GET1 GHR GJB1 GORAB HSD17B11 HSD17B13 LIME1 LMNA MAL2 NSF PBX3 PEX12 PLIN3 REEP6 RTN3 SCAMP1 SLC16A13 SLC30A8 SLC7A1 SPAG4 STX6 SYP TMCO2 TMEM80 TMEM86B TMX2 YIF1A	107 interacting genes: ABHD16A ADGRE2 ADIPOQ AP1M1 APOD ASPH BET1 BMP10 BRICD5 C3orf52 CD81 CDIPT CDS2 CERCAM CFTR CIAO2A CLCA4 CLDN19 CNIH1 CTSA CXCL16 CYB561D2 CYB5B DIABLO ERMP1 FAM3C FARS2 GET3 H4C7 HHATL HMOX1 HSBP1L1 HTATIP2 IER3 IFITM3 IGFBP5 IRF2 JOSD2 LAT LNPEP MAN2B2 MIEF2 MRM1 NFU1 NKG7 NPFFR2 OCIAD1 OXNAD1 PBX3 PCYT1A PEX16 PEX19 PLLP PLP1 PLP2 PLPP6 PPIF PRMT6 PTCD1 PTPN9 RBFA RPRM RUSF1 SELENOK SERP1 SGTA SLC30A3 SLC38A7 SLC7A14 SNX1 SNX12 STATH STX7 STX8 SUCLA2 TARS2 TCP11X2 TECR TF THAP4 THSD7B TMEM108 TMEM120B TMEM147 TMEM14A TMEM229B TMEM239 TMEM54 TMEM86A TMEM86B TMEM97 TRAM1L1 TSPAN2 TSPO2 TTPA TXNDC12 UBIAD1 UBQLN4 UNC93B1 UPK1B UPK2 VSTM4 WFDC2 WIPI2 YIPF4 YIPF6 ZFPL1
Entrez ID		5780	51661
HPRD ID		02864	08451
Ensembl ID		ENSG00000169410	ENSG00000079150
Uniprot IDs		P43378 Q6IQ43	B4DRE2 Q9Y680
PDB IDs		2PA5 4GE2 4GE5 4GE6 4ICZ 6KZQ 6L03
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Steroid Dehydrogenase Activity Endoplasmic Reticulum Tubular Network Formation Protein Binding Endoplasmic Reticulum Tubular Network Membrane Organization Syntaxin Binding Non-motile Cilium Assembly	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Protein Binding Chloride Channel Inhibitor Activity Regulation Of Cellular Localization Cellular Localization Protein Insertion Into ER Membrane Transferrin Receptor Binding Alkenylglycerophosphocholine Hydrolase Activity Lysosome Peroxisome Membrane Biogenesis Intraciliary Transport Particle B Binding Cholesterol Binding Establishment Of Localization In Cell
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