IL36RN and SSBP2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IL36RN	SSBP2
Gene Name		interleukin 36 receptor antagonist	single-stranded DNA binding protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space	Nucleus Cytoplasm
	Molecular Function	Cytokine Activity Interleukin-1 Receptor Binding Interleukin-1 Receptor Antagonist Activity	Single-stranded DNA Binding
	Biological Process	Negative Regulation Of Cytokine-mediated Signaling Pathway Cytokine-mediated Signaling Pathway Antifungal Humoral Response Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-6 Production Innate Immune Response Negative Regulation Of Interferon-gamma Secretion	Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Anorexia nervosa ( 21079607) Glioblastoma ( 22472174)
Protein-Protein Interactions		7 interactors: MCM6 REL SKIL SSBP2 SSBP3 SSBP4 ZNF512B	6 interactors: CDK6 EWSR1 IL36RN LDB1 LDB2 TOM1
Entrez ID		26525	23635
HPRD ID		16112	09577
Ensembl ID		ENSG00000136695
Uniprot IDs		Q9UBH0	P81877
PDB IDs
Enriched GO Terms of Interacting Partners?		Prechordal Plate Formation Midbrain-hindbrain Boundary Initiation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Anterior Head Development Neural Plate Anterior/posterior Regionalization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Protein Heterotrimerization Midbrain-hindbrain Boundary Development Nitrogen Compound Metabolic Process DNA Unwinding Involved In DNA Replication RNA Metabolic Process Regulation Of Interleukin-12 Biosynthetic Process Protein Homotrimerization Rostrocaudal Neural Tube Patterning Gene Expression Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors DNA Strand Elongation Involved In DNA Replication Regulation Of Transcription From RNA Polymerase II Promoter DNA Strand Elongation Lens Fiber Cell Differentiation DNA Replication Initiation Protein Trimerization Blastocyst Formation Head Morphogenesis NIK/NF-kappaB Signaling Positive Regulation Of Interleukin-12 Production Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Immune System Process Response To Cytokine Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Chordate Embryonic Development Body Morphogenesis	Epithelial Structure Maintenance Regulation Of Erythrocyte Differentiation Stem Cell Differentiation Somatic Stem Cell Maintenance Negative Regulation Of Myeloid Cell Differentiation Hair Follicle Development Hair Cycle Process Histone H3-K4 Acetylation Cell Dedifferentiation Negative Regulation Of Interferon-gamma Secretion Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Hair Cycle Antifungal Humoral Response Positive Regulation Of Hemoglobin Biosynthetic Process Negative Regulation Of Cell Differentiation Stem Cell Maintenance Regulation Of Myeloid Cell Differentiation Tissue Homeostasis Regulation Of Hemoglobin Biosynthetic Process Skin Development Multicellular Organismal Homeostasis Stem Cell Development Epithelium Development Epidermis Development Negative Regulation Of Cellular Senescence Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Interleukin-17 Production Hematopoietic Stem Cell Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of Immune System Process Negative Regulation Of Cell Aging Cerebellar Purkinje Cell Differentiation Extracellular Negative Regulation Of Signal Transduction Cerebellar Purkinje Cell Layer Morphogenesis Dentate Gyrus Development Type B Pancreatic Cell Development Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Astrocyte Development Type B Pancreatic Cell Differentiation Negative Regulation Of Receptor Activity Lateral Ventricle Development Enteroendocrine Cell Differentiation Regulation Of Cellular Senescence Tissue Development Cerebellar Cortex Formation Defense Response To Fungus Antimicrobial Humoral Response Cell Development Glandular Epithelial Cell Development
Tagcloud ?			abstract aim apc area assessment biomarkers cdkn2a chile cholecystitis cohort curve dna elisa esr1 gallbladder gbc global index material methylation operator pgp9 predictive promoter quantitative receiver specificity technique useful
Tagcloud (Difference) ?			abstract aim apc area assessment biomarkers cdkn2a chile cholecystitis cohort curve dna elisa esr1 gallbladder gbc global index material methylation operator pgp9 predictive promoter quantitative receiver specificity technique useful
Tagcloud (Intersection) ?