SPRYD7 and PDZD3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SPRYD7	PDZD3
Gene Name		SPRY domain containing 7	PDZ domain containing 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Cytosol Brush Border Subapical Complex Apical Part Of Cell
	Molecular Function		Protein Binding Protein C-terminus Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity
	Biological Process		Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance CGMP-mediated Signaling Negative Regulation Of CGMP Biosynthetic Process Negative Regulation Of Guanylate Cyclase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CAMK2B PDZD3 TRIP13 VAC14	17 interactors: ABCC2 ASAP3 CACNA1S CFTR GUCY2C PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7
Entrez ID		57213	79849
HPRD ID		08486	06191
Ensembl ID		ENSG00000123178	ENSG00000172367
Uniprot IDs		Q5W111	B0YJ61 Q86UT5
PDB IDs			2V90
Enriched GO Terms of Interacting Partners?		Negative Regulation Of CGMP Biosynthetic Process Negative Regulation Of Guanylate Cyclase Activity Inhibitory G-protein Coupled Receptor Phosphorylation Activation Of Meiosis Involved In Egg Activation Activation Of Meiosis Regulation Of Synaptic Transmission, Cholinergic Regulation Of Skeletal Muscle Adaptation CGMP-mediated Signaling Receptor Guanylyl Cyclase Signaling Pathway Regulation Of Synapse Structural Plasticity Female Meiosis I Positive Regulation Of Dendritic Spine Morphogenesis Positive Regulation Of Synapse Maturation Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Meiotic Nuclear Division Egg Activation Regulation Of Synapse Maturation Regulation Of CGMP Biosynthetic Process Synaptonemal Complex Assembly Negative Regulation Of Lyase Activity Oocyte Maturation Synaptonemal Complex Organization Positive Regulation Of Dendritic Spine Development Regulation Of Cellular Response To Heat Male Meiosis I Cyclic-nucleotide-mediated Signaling Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of CGMP Metabolic Process Regulation Of Dendritic Spine Morphogenesis Cellular Response To Stimulus Female Meiotic Division Positive Regulation Of Dendrite Morphogenesis Sexual Reproduction Negative Regulation Of Nucleotide Metabolic Process Regulation Of Meiosis Water Transport Reciprocal Meiotic Recombination Oocyte Development Oocyte Differentiation Fluid Transport Regulation Of Dendritic Spine Development Regulation Of Meiotic Cell Cycle Synapsis Regulation Of Lipid Kinase Activity Regulation Of Neuronal Synaptic Plasticity Homologous Chromosome Segregation Response To Cadmium Ion Positive Regulation Of Dendrite Development Male Meiosis Reproduction	Transmembrane Transport Ion Transport Ion Transmembrane Transport Sodium-independent Organic Anion Transport Anion Transport Organic Anion Transport Anion Transmembrane Transport Drug Transport Monocarboxylic Acid Transport Quaternary Ammonium Group Transport Transport Cation Transmembrane Transport Drug Transmembrane Transport Carboxylic Acid Transport Organic Acid Transport Antibiotic Transport Toxin Transport Ammonium Transmembrane Transport Organic Cation Transport Cation Transport Oligopeptide Transport Ammonium Transport Response To Drug Inorganic Anion Transport Carnitine Transmembrane Transport Carnitine Transport Lipid Transport Lipid Localization Monovalent Inorganic Cation Transport Dipeptide Transport Histamine Uptake Positive Regulation Of ARF GTPase Activity Short-chain Fatty Acid Import Positive Regulation Of Voltage-gated Chloride Channel Activity Positive Regulation Of Intestinal Epithelial Structure Maintenance Quorum Sensing Involved In Interaction With Host Sodium-dependent Organic Cation Transport Fatty Acid Transport Regulation Of Intestinal Epithelial Structure Maintenance Prostaglandin Transport Peptide Transport Hormone Transport Extraocular Skeletal Muscle Development Oligopeptide Transmembrane Transport Regulation Of Chloride Transport Amide Transport Iodide Transport Thyroid Hormone Transport Transepithelial Chloride Transport Cellular Chloride Ion Homeostasis
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