FLNB and ASB2

Number of citations of the paper that reports this interaction (PMID 19300455)
14

Data Source:
BioGRID (enzymatic study)

		FLNB	ASB2
Gene Name		filamin B, beta	ankyrin repeat and SOCS box containing 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Cytoplasm Cytosol Plasma Membrane Focal Adhesion Cell Cortex Actin Cytoskeleton Integral Component Of Membrane Z Disc Extracellular Vesicular Exosome	Cul5-RING Ubiquitin Ligase Complex
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Cytoskeletal Anchoring At Plasma Membrane Signal Transduction Skeletal Muscle Tissue Development Cytokine-mediated Signaling Pathway Actin Cytoskeleton Organization Cell Differentiation	Protein Polyubiquitination Signal Transduction Intracellular Signal Transduction Skeletal Muscle Cell Differentiation Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Myoblast Differentiation
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065) Eating disorders (purging via substances) ( 23568457)
Protein-Protein Interactions		17 interactors: ASB2 ATF7IP FBLIM1 FLNA GP1BA ITGB1 ITGB3 ITGB6 MLH1 NPHP1 PLEKHO1 PSEN1 PSEN2 RAD21 SMURF2 TRIM55 TSHR	7 interactors: FLNA FLNB RNF7 SMAD9 TCEB2 UBC UBE2D1
Entrez ID		2317	51676
HPRD ID		04543	05768
Ensembl ID		ENSG00000136068	ENSG00000100628
Uniprot IDs		E7EN95 O75369	Q96Q27
PDB IDs		2DI8 2DI9 2DIA 2DIB 2DIC 2DJ4 2DLG 2DMB 2DMC 2E9I 2E9J 2EE6 2EE9 2EEA 2EEB 2EEC 2EED 2WA5 2WA6 2WA7 3FER 4B7L
Enriched GO Terms of Interacting Partners?		Cell Activation Cell Adhesion Single Organismal Cell-cell Adhesion Signal Transduction Cellular Response To Stimulus Signaling Cell Communication Viral Entry Into Host Cell Entry Into Host Cell Lymphocyte Activation Cell Junction Assembly Regulation Of Peptidyl-tyrosine Phosphorylation Single-organism Behavior Cell Development Leukocyte Activation Amyloid Precursor Protein Catabolic Process Regulation Of Cellular Process Response To Stimulus Neuron Development Cell Fate Specification Behavior Interaction With Host Embryonic Morphogenesis Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process Cell Surface Receptor Signaling Pathway Homotypic Cell-cell Adhesion Leukocyte Differentiation Neuron Differentiation Integrin-mediated Signaling Pathway Tissue Development Cell Projection Organization Immune System Development Membrane Protein Ectodomain Proteolysis Notch Receptor Processing Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Signal Transduction Cell Differentiation Heterotypic Cell-cell Adhesion Regulation Of Epidermal Growth Factor-activated Receptor Activity Response To Stress Developmental Process Leukocyte Activation Involved In Immune Response B Cell Activation Blood Coagulation Cell-matrix Adhesion Hemostasis Endoplasmic Reticulum Calcium Ion Homeostasis	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Response To Hypoxia Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Transforming Growth Factor Beta Receptor Signaling Pathway Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transcription From RNA Polymerase II Promoter Response To Stress Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Cellular Response To Stimulus Response To Abiotic Stimulus TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Transcription, DNA-templated MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway RNA Biosynthetic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity BMP Signaling Pathway Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Ubiquitination Toll-like Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Cellular Response To Stress Negative Regulation Of Protein Catabolic Process Response To Growth Factor Response To Stimulus Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Cell Surface Receptor Signaling Pathway Signal Transduction Mitotic Cell Cycle Process RNA Metabolic Process Activation Of Innate Immune Response
Tagcloud ?		actionable algorithms asf1 assuming candidates distinguishing driver genomes grm1 hcf1 hierarchically interpreting involve machinery modules neutral organized passenger pou2f1 precisely presents prkcz psnv psnvs snvs thousands uncovered unexpectedly ways	ablating accelerating ankyrin associate associates box bridges cul cul1 cul5 cullin demanding dimeric dn e2a e3 elonginb exerts monomeric notch partly shifting sirnas skp1 skp2 socs transcriptionally turnover versatile
Tagcloud (Difference) ?		actionable algorithms asf1 assuming candidates distinguishing driver genomes grm1 hcf1 hierarchically interpreting involve machinery modules neutral organized passenger pou2f1 precisely presents prkcz psnv psnvs snvs thousands uncovered unexpectedly ways	ablating accelerating ankyrin associate associates box bridges cul cul1 cul5 cullin demanding dimeric dn e2a e3 elonginb exerts monomeric notch partly shifting sirnas skp1 skp2 socs transcriptionally turnover versatile
Tagcloud (Intersection) ?