NXT2 and CEP63

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NXT2	CEP63
Gene Name		nuclear transport factor 2-like export factor 2	centrosomal protein 63kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Spindle Pole Centrosome Centriole Cytosol
	Molecular Function		Protein Binding
	Biological Process	Protein Transport MRNA Transport	DNA Damage Checkpoint G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Centriole Replication Signal Transduction In Response To DNA Damage Spindle Assembly Cell Division
Pathways			Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Height ( 18391952)
Protein-Protein Interactions		16 interactors: APP CCDC102B CEP63 GOLGA2 LNX1 NXF1 NXF2 NXF3 PKM PTPN3 REL SRPK1 SRPK2 SSBP3 TRIM23 USP54	44 interactors: ALOX5 ARFIP2 ARNT2 CAMKK2 CCDC14 CCNI CEP57 CEP57L1 DDX26B DISC1 DST DTNB DZIP3 EXOC4 EZH2 FAM161A FBF1 GSE1 HAUS1 KXD1 MACF1 MBIP NCOR2 NDEL1 NXT2 PCNXL4 POLR3C PPP1R13B PPP4R1 SMARCE1 SMC3 SNRNP70 SPTAN1 SPTBN1 SSX3 SYNE1 SYT17 TANK TBC1D15 TSHZ3 TXLNA TXLNB USHBP1 ZCCHC10
Entrez ID		55916	80254
HPRD ID		02264	07826
Ensembl ID		ENSG00000101888	ENSG00000182923
Uniprot IDs		Q9NPJ8	Q96MT8
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Export From Nucleus RNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus MRNA Transport Nuclear Export RNA Transport Positive Regulation Of Viral Genome Replication RNA Localization Negative Regulation Of Viral Genome Replication Gene Expression Nucleocytoplasmic Transport Nuclear Transport Nuclear Speck Organization Midbrain-hindbrain Boundary Initiation Prechordal Plate Formation Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Innate Immune Response Synaptic Growth At Neuromuscular Junction Positive Regulation Of Anterior Head Development Regulation Of MRNA Processing Regulation Of RNA Splicing Collateral Sprouting In Absence Of Injury MRNA Processing Neural Plate Anterior/posterior Regionalization Liver Regeneration Nucleus Organization Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Membrane Depolarization During Action Potential Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Membrane Protein Ectodomain Proteolysis Regulation Of Protein Binding MRNA Metabolic Process Regulation Of Viral Process Axon Choice Point Recognition Intracellular Signal Transduction Viral Process Cellular Component Assembly RNA Processing Neuron Remodeling Sperm Chromatin Condensation Immune Response Centriole Replication Positive Regulation Of Interleukin-12 Biosynthetic Process Defense Response Immune System Process Midbrain-hindbrain Boundary Development	Microtubule Cytoskeleton Organization Organelle Organization Cytoskeleton Organization Microtubule-based Process Cell Cycle Process Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Cell Cycle Cellular Localization Golgi To Plasma Membrane Protein Transport Cell Cycle Maintenance Of Protein Location In Cell Maintenance Of Protein Location Brain Development Maintenance Of Location In Cell Protein Localization To Organelle Head Development Anatomical Structure Development Golgi To Plasma Membrane Transport Regulation Of Cellular Component Size Positive Regulation Of Axon Extension Intermediate Filament Cytoskeleton Organization Microtubule Anchoring Protein Localization Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Leukotriene Production Involved In Inflammatory Response Kidney Smooth Muscle Cell Differentiation Ureteric Peristalsis Nervous System Development Intermediate Filament-based Process Positive Regulation Of Cell Morphogenesis Involved In Differentiation Protein Localization To Nucleus Regulation Of Cell Cycle Cell Proliferation In Forebrain Actin Filament Capping Central Nervous System Development Mitotic Cell Cycle Process Cellular Protein Localization Cerebral Cortex Radially Oriented Cell Migration Endomembrane System Organization Negative Regulation Of Actin Filament Depolymerization Developmental Process
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