NXT2 and NXF3

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (in vitro)

		NXT2	NXF3
Gene Name		nuclear transport factor 2-like export factor 2	nuclear RNA export factor 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Cytoplasm Nuclear RNA Export Factor Complex
	Molecular Function		Nucleotide Binding MRNA Binding Protein Binding
	Biological Process	Protein Transport MRNA Transport	MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: APP CCDC102B CEP63 GOLGA2 LNX1 NXF1 NXF2 NXF3 PKM PTPN3 REL SRPK1 SRPK2 SSBP3 TRIM23 USP54	7 interactors: HNRNPUL1 NUP214 NXF1 NXT1 NXT2 SKIL XPO1
Entrez ID		55916	56000
HPRD ID		02264	02261
Ensembl ID		ENSG00000101888	ENSG00000147206
Uniprot IDs		Q9NPJ8	Q9H4D5
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Export From Nucleus RNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus MRNA Transport Nuclear Export RNA Transport Positive Regulation Of Viral Genome Replication RNA Localization Negative Regulation Of Viral Genome Replication Gene Expression Nucleocytoplasmic Transport Nuclear Transport Nuclear Speck Organization Midbrain-hindbrain Boundary Initiation Prechordal Plate Formation Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Innate Immune Response Synaptic Growth At Neuromuscular Junction Positive Regulation Of Anterior Head Development Regulation Of MRNA Processing Regulation Of RNA Splicing Collateral Sprouting In Absence Of Injury MRNA Processing Neural Plate Anterior/posterior Regionalization Liver Regeneration Nucleus Organization Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Membrane Depolarization During Action Potential Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Membrane Protein Ectodomain Proteolysis Regulation Of Protein Binding MRNA Metabolic Process Regulation Of Viral Process Axon Choice Point Recognition Intracellular Signal Transduction Viral Process Cellular Component Assembly RNA Processing Neuron Remodeling Sperm Chromatin Condensation Immune Response Centriole Replication Positive Regulation Of Interleukin-12 Biosynthetic Process Defense Response Immune System Process Midbrain-hindbrain Boundary Development	RNA Transport RNA Localization Nuclear Export MRNA Transport Protein Export From Nucleus Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus Cytoplasmic Transport MRNA Export From Nucleus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Viral Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Establishment Of Protein Localization Intracellular Transport Transforming Growth Factor Beta Receptor Signaling Pathway Ribosomal Small Subunit Export From Nucleus Protein Localization To Nucleus Gene Expression Protein Localization Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Viral Life Cycle Response To Transforming Growth Factor Beta Establishment Of Localization In Cell Intracellular Protein Transport Regulation Of Cell Cycle Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Ribosomal Large Subunit Export From Nucleus Ribosomal Subunit Export From Nucleus Poly(A)+ MRNA Export From Nucleus Cellular Localization Protein Heterotrimerization Cellular Protein Localization Cell Cycle Protein Homotrimerization Transport Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Protein Export From Nucleus Intracellular Transport Of Virus Protein Localization To Organelle Lens Fiber Cell Differentiation Protein Trimerization Mitotic Nuclear Envelope Disassembly Regulation Of Centrosome Duplication Cellular Response To Growth Factor Stimulus
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