NXT2 and SSBP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NXT2	SSBP3
Description		nuclear transport factor 2 like export factor 2	single stranded DNA binding protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear RNA Export Factor Complex Nuclear Pore Central Transport Channel Perinuclear Region Of Cytoplasm	Nucleus Transcription Regulator Complex Protein-containing Complex
	Molecular Function	Protein Binding	DNA Binding Single-stranded DNA Binding Transcription Coactivator Activity Protein Binding
	Biological Process	MRNA Export From Nucleus Nucleocytoplasmic Transport Protein Transport Poly(A)+ MRNA Export From Nucleus MRNA Transport	Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Cell Population Proliferation Prechordal Plate Formation Midbrain-hindbrain Boundary Initiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Mesendoderm Development Head Development Head Morphogenesis Protein-containing Complex Assembly Positive Regulation Of Anterior Head Development
Pathways
Drugs
Diseases
GWAS			Adult body size ( 32376654) Blood urea nitrogen levels ( 29403010 31152163) Body mass index ( 25673413) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Food allergy ( 25710614) Liver enzyme levels (alkaline phosphatase) ( 33972514) Menarche (age at onset) ( 27182965) Monocyte count ( 32888494) P wave duration ( 28794112) Platelet distribution width ( 32888494 27863252) PR interval ( 32439900) Refractive error ( 32231278) Serum bilirubin levels in metabolic syndrome ( 30621171) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) TPE interval (resting) ( 32386560) Triglyceride levels ( 32203549 32154731)
Interacting Genes		24 interacting genes: APP CCDC102B CEP63 DDIT4L GOLGA2 GOLGA6L9 IKZF3 LNX1 NXF1 NXF2 NXF2B NXF3 PKM PTPN3 RASSF10 REL SRPK1 SRPK2 SSBP3 STAT3 TCF4 TRIM23 USP54 ZNF655	20 interacting genes: ANKEF1 APP ARNT2 BLK CLK1 DTNB EWSR1 HCLS1 IL36RN LDB1 LDB2 NXT2 PIN1 RFC1 SIVA1 SS18L1 SUPT5H TBC1D23 YES1 ZNF226
Entrez ID		55916	23648
HPRD ID		02264	09578
Ensembl ID		ENSG00000101888	ENSG00000157216
Uniprot IDs		Q9NPJ8	Q9BWW4 Q9NW25
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear RNA Export Factor Complex Poly(A)+ MRNA Export From Nucleus MRNA Export From Nucleus RNA Export From Nucleus Cytoplasm Nuclear Transport Nucleocytoplasmic Transport MRNA Transport Nuclear Export RNA Transport Intracellular Transport Nucleobase-containing Compound Transport Innate Immune Response Defense Response To Symbiont Protein Serine/threonine Kinase Binding Defense Response To Other Organism Response To Other Organism Regulation Of Membrane Protein Ectodomain Proteolysis Cellular Localization Establishment Of Localization In Cell RNA Binding Positive Regulation Of Viral Genome Replication Amyloid-beta Complex Immune Response Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of ATP Metabolic Process Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Spindle Pole Prechordal Plate Formation Midbrain-hindbrain Boundary Initiation	Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Non-membrane Spanning Protein Tyrosine Kinase Activity Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process LIM Domain Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Enzyme Binding Negative Regulation Of Transcription By RNA Polymerase II Antifungal Humoral Response Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Transcription Regulator Complex Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Protein Tyrosine Kinase Activity Transcription Coregulator Activity Regulation Of Macromolecule Metabolic Process Nucleus Regulation Of Primary Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Protein Localization To Nucleus Epithelial Structure Maintenance Positive Regulation Of Macromolecule Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Dendrite Development Cis-trans Isomerase Activity Hair Follicle Development CD27 Receptor Binding Regulation Of Metabolic Process Regulation Of Amyloid Precursor Protein Catabolic Process Defense Response To Fungus Acetylcholine Receptor Activator Activity Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Response To Fungus Lipoprotein Particle
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