KYAT1

Description		kynurenine aminotransferase 1
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding Transaminase Activity Kynurenine-oxoglutarate Transaminase Activity Transferase Activity Lyase Activity Pyridoxal Phosphate Binding Protein Homodimerization Activity Glutamine-phenylpyruvate Transaminase Activity Cysteine-S-conjugate Beta-lyase Activity
	Biological Process	Response To Bacterium Kynurenine Metabolic Process L-kynurenine Catabolic Process
Pathways		Tryptophan catabolism Phenylalanine metabolism Glutamate and glutamine metabolism
Drugs		Pyridoxal phosphate Pyridoxamine-5'-Phosphate D-Phenylalanine N(6)-(pyridoxal phosphate)-L-lysine Indoleacetic acid
Diseases
GWAS
Interacting Genes		5 interacting genes: APP TRIM55 TRIM63 TRIP13 VAC14
Entrez ID		883
HPRD ID		02769
Ensembl ID		ENSG00000171097
Uniprot IDs		A0A494C066 A8K563 B7Z4W5 Q16773
PDB IDs		1W7L 1W7M 1W7N 3FVS 3FVU 3FVX 4WLH 4WLJ 4WP0
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Response To Interleukin-1 Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Amylin Binding Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Toll Signaling Pathway Regulation Of Receptor Internalization Positive Regulation Of Non-canonical NF-kappaB Signal Transduction PAS Complex Regulation Of Non-canonical NF-kappaB Signal Transduction Acetylcholine Receptor Activator Activity PTB Domain Binding Innate Immune Response Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Defense Response To Symbiont Defense Response To Other Organism Endosome To Plasma Membrane Transport Vesicle Cell Maturation Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Receptor-mediated Endocytosis Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Generation Of Precursor Metabolites And Energy Identical Protein Binding Meiotic Recombination Checkpoint Signaling Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Signal Transduction Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Developmental Maturation Early Endosome Membrane Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Skeletal Muscle Atrophy Regulation Of Spontaneous Synaptic Transmission
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