DPPA4 and LDOC1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		DPPA4	LDOC1
Gene Name		developmental pluripotency associated 4	leucine zipper, down-regulated in cancer 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleolus
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Lung-associated Mesenchyme Development	Negative Regulation Of Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Corneal astigmatism ( 23761726)
Protein-Protein Interactions		17 interactors: BTBD2 CRK DPPA2 EIF4A2 EMD GRB2 HTT LDOC1 MAPK6 PTPRO QARS RPGRIP1 RPS6KB1 SH3GL1 SH3GL2 SH3GL3 VIM	62 interactors: AATF ABLIM1 AEBP2 AES AP1M1 ATF4 ATP6V1G1 BARD1 C1orf109 CCDC33 CCDC85B CEBPE CTNNBL1 DPF2 DPPA4 FAM107A FAM193B FAM208B FAM50B FAM90A1 FOSL1 FXR2 GNL3L HAUS1 HDAC4 HGS IKZF5 INPP1 KRT15 KRT18 LATS1 LENG1 LNX1 MEAF6 MFAP1 MYC MZF1 NRIP1 NXF1 PEG10 PLEKHF2 POLL PRPF31 PSMA1 PSMF1 RAB29 SDCBP SETD5 SH2D4A SMARCD1 TBC1D7 TMSB4XP1 TNNT1 TTC23 UTP14A ZBTB16 ZBTB24 ZGPAT ZNF250 ZNF408 ZNF564 ZNF774
Entrez ID		55211	23641
HPRD ID		16836	02322
Ensembl ID		ENSG00000121570	ENSG00000182195
Uniprot IDs		Q7L190	O95751
PDB IDs
Enriched GO Terms of Interacting Partners?		Nervous System Development Anatomical Structure Development Cell Development System Development Response To Organic Substance Cellular Response To Organic Substance Cellular Response To Stimulus Developmental Process Enzyme Linked Receptor Protein Signaling Pathway Response To Stimulus Central Nervous System Development Cellular Response To Growth Factor Stimulus Multicellular Organismal Development Response To Growth Factor Endocytosis Tissue Development Signal Transduction Cell Differentiation Insulin Receptor Signaling Pathway Signaling Cell Communication Cellular Response To Organonitrogen Compound Vesicle-mediated Transport Regulation Of Cell Proliferation Movement Of Cell Or Subcellular Component Regulation Of Cellular Process Negative Regulation Of Neuron Differentiation Response To Hormone Organ Development Neuron Development Generation Of Neurons Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Muscle Contraction Cell Surface Receptor Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neurogenesis Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Signal Transduction Neuron Differentiation Muscle System Process Neural Plate Formation Glutaminyl-tRNA Aminoacylation Negative Regulation Of RNA-directed RNA Polymerase Activity Slit Diaphragm Assembly Regulation Of Translation Negative Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Cell Proliferation	Gene Expression Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Apoptotic Process Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Programmed Cell Death Cell Death Death Negative Regulation Of Gene Expression Regulation Of Cellular Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Apoptotic Process Biosynthetic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Gene Expression Regulation Of Cell Death Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Negative Regulation Of Wnt Signaling Pathway Melanosome Organization Pigment Granule Organization
Tagcloud ?		assembled binds biochemical chromatin developmental digestion dynamics embryonic es frap h1 h3 histone immunoprecipitation implies micrococcal mnase mobility modulates nuclease nuclei photobleaching pluripotency poorly proper recovery truncated uncharacterized understood	abcc5 cabpr cbr3 clonogenic comprehensive differentially dock8 dsc2 esophageal extracted fabp5 global gpx2 hence know microarray ndn nme oligonucleotide radiation radioresistant radiosensitive radiosensitivities radiosensitivity radiotherapy rpa1 skp1a spot te
Tagcloud (Difference) ?		assembled binds biochemical chromatin developmental digestion dynamics embryonic es frap h1 h3 histone immunoprecipitation implies micrococcal mnase mobility modulates nuclease nuclei photobleaching pluripotency poorly proper recovery truncated uncharacterized understood	abcc5 cabpr cbr3 clonogenic comprehensive differentially dock8 dsc2 esophageal extracted fabp5 global gpx2 hence know microarray ndn nme oligonucleotide radiation radioresistant radiosensitive radiosensitivities radiosensitivity radiotherapy rpa1 skp1a spot te
Tagcloud (Intersection) ?