LDOC1 and ZNF648

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LDOC1	ZNF648
Description		LDOC1 regulator of NFKB signaling	zinc finger protein 648
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Maternal Placenta Development Negative Regulation Of Cell Population Proliferation Maternal Process Involved In Parturition Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Cardiovascular heart disease in diabetics ( 23982368) HDL cholesterol ( 24097068 25961943 20686565) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 33339817) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Morning person ( 30696823) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
Interacting Genes		106 interacting genes: AATF ABLIM1 AEBP2 AIRIM AP1M1 AQP1 ATF4 ATP6V1G1 BARD1 BEX2 BYSL CCDC33 CCDC85B CDC5L CEBPE CFAP53 CTNNBL1 DPF2 DPPA4 ENKD1 FAM107A FAM110A FAM161A FAM193B FAM50B FAM90A1 FCHSD2 FOSL1 FXR2 GADD45GIP1 GNL3L GPANK1 HAUS1 HDAC4 HGS HOXB5 HOXC8 IKZF3 IKZF5 INPP1 IQCB1 JRK KRT15 KRT18 LATS1 LENG1 LMO2 LNX1 MBD3 MEAF6 MFAP1 MSGN1 MYC MZF1 NOD2 NRIP1 NXF1 PLEKHF2 POLL PPP1R18 PRPF18 PRPF31 PSMA1 PSMF1 RAB29 RALBP1 RASSF10 RIBC1 RNF6 RPP25 SCNM1 SDCBP SETD5 SH2D4A SMARCB1 SMARCD1 SUDS3 TASOR2 TBC1D7 TCEANC TEAD4 THAP7 TLE5 TMSB4XP1 TNNT1 TSGA10IP TSNAX TTC23 UBTFL1 UTP14A WDR25 WT1 ZBTB16 ZBTB24 ZFP1 ZGPAT ZNF124 ZNF250 ZNF408 ZNF564 ZNF587 ZNF629 ZNF648 ZNF688 ZNF774 ZNF835	62 interacting genes: AXIN2 BEGAIN BICD2 CALCOCO2 CARD14 CCDC120 CCDC136 CCDC57 CDR2L CEP70 CYSRT1 DVL3 EVI5L FSD2 GOLGA2 GOLGA6L9 HAP1 HOOK2 HSF2BP KANK2 KRT31 KRTAP1-1 KRTAP10-8 KRTAP12-3 LDOC1 LZTS2 MCC MDFI MEOX2 MID2 MTUS2 NBPF19 NOTCH2NLA NUDT22 OSBPL3 PLEKHG4 RBAK RINT1 RUBCN SSX2IP SYNE4 TEX19 TNS2 TRAF1 TRAF2 TRIM41 ZBTB8A ZCCHC13 ZNF250 ZNF260 ZNF275 ZNF317 ZNF343 ZNF438 ZNF552 ZNF620 ZNF655 ZNF71 ZNF768 ZNF792 ZNF837 ZRANB1
Entrez ID		23641	127665
HPRD ID		02322	18361
Ensembl ID		ENSG00000182195	ENSG00000179930
Uniprot IDs		O95751	Q5T619
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Nucleoplasm DNA-binding Transcription Factor Activity Nuclear Speck Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Stem Cell Population Maintenance Zinc Ion Binding Positive Regulation Of Stem Cell Population Maintenance DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Spindle Pole DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Transcription By RNA Polymerase II Chromatin NBAF Complex Positive Regulation Of RNA Biosynthetic Process Centrosome Positive Regulation Of DNA-templated Transcription Chromatin Organization Cytoskeleton Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Protein-DNA Complex Disassembly Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Remodeling Regulation Of Nucleotide-excision Repair Ribosome Biogenesis SWI/SNF Complex Positive Regulation Of Transcription By RNA Polymerase I Spliceosomal Complex	Zinc Ion Binding Protein Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
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