LDOC1 and DPF2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		LDOC1	DPF2
Description		LDOC1 regulator of NFKB signaling	double PHD fingers 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol SWI/SNF Complex NBAF Complex
	Molecular Function	Protein Binding	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding Histone H3K9me2/3 Reader Activity Histone H3K14ac Reader Activity Histone H4K16ac Reader Activity
	Biological Process	Maternal Placenta Development Negative Regulation Of Cell Population Proliferation Maternal Process Involved In Parturition Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Apoptotic Process Nervous System Development Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of G0 To G1 Transition Apoptotic Signaling Pathway Positive Regulation Of Stem Cell Population Maintenance Negative Regulation Of Myeloid Progenitor Cell Differentiation Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Double-strand Break Repair Regulation Of Nucleotide-excision Repair
Pathways			Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the canonical BAF (cBAF) complex Formation of the embryonic stem cell BAF (esBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Mean spheric corpuscular volume ( 32888494) Urate levels ( 31578528)
Interacting Genes		106 interacting genes: AATF ABLIM1 AEBP2 AIRIM AP1M1 AQP1 ATF4 ATP6V1G1 BARD1 BEX2 BYSL CCDC33 CCDC85B CDC5L CEBPE CFAP53 CTNNBL1 DPF2 DPPA4 ENKD1 FAM107A FAM110A FAM161A FAM193B FAM50B FAM90A1 FCHSD2 FOSL1 FXR2 GADD45GIP1 GNL3L GPANK1 HAUS1 HDAC4 HGS HOXB5 HOXC8 IKZF3 IKZF5 INPP1 IQCB1 JRK KRT15 KRT18 LATS1 LENG1 LMO2 LNX1 MBD3 MEAF6 MFAP1 MSGN1 MYC MZF1 NOD2 NRIP1 NXF1 PLEKHF2 POLL PPP1R18 PRPF18 PRPF31 PSMA1 PSMF1 RAB29 RALBP1 RASSF10 RIBC1 RNF6 RPP25 SCNM1 SDCBP SETD5 SH2D4A SMARCB1 SMARCD1 SUDS3 TASOR2 TBC1D7 TCEANC TEAD4 THAP7 TLE5 TMSB4XP1 TNNT1 TSGA10IP TSNAX TTC23 UBTFL1 UTP14A WDR25 WT1 ZBTB16 ZBTB24 ZFP1 ZGPAT ZNF124 ZNF250 ZNF408 ZNF564 ZNF587 ZNF629 ZNF648 ZNF688 ZNF774 ZNF835	20 interacting genes: FHL2 GOLGA6L9 H3-4 H3C1 H4C1 HSF2BP LDOC1 LNX1 MEOX2 NFKB2 PICK1 REL RELB RINT1 RUBCN TTC23L TXNDC12 UPF2 ZNF212 ZNF655
Entrez ID		23641	5977
HPRD ID		02322	03394
Ensembl ID		ENSG00000182195	ENSG00000133884
Uniprot IDs		O95751	J3KMZ8 Q92785
PDB IDs			3IUF 5B79 5VDC 6LTH 6LTJ
Enriched GO Terms of Interacting Partners?		Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Nucleoplasm DNA-binding Transcription Factor Activity Nuclear Speck Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Stem Cell Population Maintenance Zinc Ion Binding Positive Regulation Of Stem Cell Population Maintenance DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Spindle Pole DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Transcription By RNA Polymerase II Chromatin NBAF Complex Positive Regulation Of RNA Biosynthetic Process Centrosome Positive Regulation Of DNA-templated Transcription Chromatin Organization Cytoskeleton Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Protein-DNA Complex Disassembly Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Remodeling Regulation Of Nucleotide-excision Repair Ribosome Biogenesis SWI/SNF Complex Positive Regulation Of Transcription By RNA Polymerase I Spliceosomal Complex	NF-kappaB Complex Non-canonical NF-kappaB Signal Transduction Canonical NF-kappaB Signal Transduction DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Interferon-beta Production Structural Constituent Of Chromatin Response To Muramyl Dipeptide Nucleosome Assembly Nucleosome Nucleosome Organization Nucleoplasm
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