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DPPA4

Description developmental pluripotency associated 4
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
Molecular Function
  • Chromatin Binding
  • Protein Binding
Biological Process
  • System Development
  • Lung-associated Mesenchyme Development
Pathways
  • POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
  • Zygotic genome activation (ZGA)
Drugs
Diseases
GWAS
  • Cardiac hypertrophy ( 21348951)
  • Corneal astigmatism ( 23761726)
  • Metabolite levels ( 23823483)
Interacting Genes 37 interacting genes: BTBD2 CIRSR CRK DPPA2 EAF1 EIF4A2 EMD FOXR1 GMPPB GRAP GRB2 GTPBP3 HTT INO80B KAT14 LDOC1 MAGOH MAP1LC3A MAP1LC3B MAPK6 MISP NEDD9 OSTF1 PLEKHF2 PTPRO QARS1 RPGRIP1 RPS6KB1 SH3GL1 SH3GL2 SH3GL3 SNX18 SNX33 SPANXN2 TLK1 TNIP1 VIM
Entrez ID 55211
HPRD ID 16836
Ensembl ID ENSG00000121570
Uniprot IDs Q7L190
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Phosphotyrosine Residue Binding
  • Cytoplasm
  • Protein Binding
  • Cellular Response To Muramyl Dipeptide
  • Cellular Response To Nitrogen Starvation
  • Cleavage Furrow Formation
  • Import Into Cell
  • Endocytosis
  • Central Nervous System Development
  • Phosphatidylethanolamine Binding
  • Plasma Membrane Tubulation
  • Organelle Organization
  • Spindle Pole Centrosome
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© Madhavi K. Ganapathiraju 2012-2025