LDOC1 and SH2D4A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LDOC1	SH2D4A
Gene Name		leucine zipper, down-regulated in cancer 1	SH2 domain containing 4A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus	Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Phosphatase Binding
	Biological Process	Negative Regulation Of Cell Proliferation	Negative Regulation Of Phosphatase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		62 interactors: AATF ABLIM1 AEBP2 AES AP1M1 ATF4 ATP6V1G1 BARD1 C1orf109 CCDC33 CCDC85B CEBPE CTNNBL1 DPF2 DPPA4 FAM107A FAM193B FAM208B FAM50B FAM90A1 FOSL1 FXR2 GNL3L HAUS1 HDAC4 HGS IKZF5 INPP1 KRT15 KRT18 LATS1 LENG1 LNX1 MEAF6 MFAP1 MYC MZF1 NRIP1 NXF1 PEG10 PLEKHF2 POLL PRPF31 PSMA1 PSMF1 RAB29 SDCBP SETD5 SH2D4A SMARCD1 TBC1D7 TMSB4XP1 TNNT1 TTC23 UTP14A ZBTB16 ZBTB24 ZGPAT ZNF250 ZNF408 ZNF564 ZNF774	43 interactors: ALAS1 CASK CCDC172 CDR2 CEP70 CEP76 DBNL FSD2 GOLGA2 GRB2 HCLS1 HMBOX1 IKZF1 KRT40 LDOC1 LZTS2 MAGEA11 MAGEA6 MTUS2 NECAB2 NINL NUTM1 PDE4DIP PNMA1 PPP1CB PSTPIP1 RINT1 SH3GL1 SKAP1 SORBS2 SORBS3 SPAG5 STAM2 STX11 TACC1 TFIP11 TRAF2 TRIM23 TRIM27 UBXN11 USHBP1 VPS52 ZBTB16
Entrez ID		23641	63898
HPRD ID		02322	08340
Ensembl ID		ENSG00000182195	ENSG00000104611
Uniprot IDs		O95751	Q9H788
PDB IDs
Enriched GO Terms of Interacting Partners?		Gene Expression Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Apoptotic Process Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Programmed Cell Death Cell Death Death Negative Regulation Of Gene Expression Regulation Of Cellular Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Apoptotic Process Biosynthetic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Gene Expression Regulation Of Cell Death Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Negative Regulation Of Wnt Signaling Pathway Melanosome Organization Pigment Granule Organization	Cell Cycle Positive Regulation Of NK T Cell Differentiation G2/M Transition Of Mitotic Cell Cycle Organelle Organization Regulation Of Cytoskeleton Organization Positive Regulation Of Granulocyte Differentiation Mitotic Cell Cycle Immune System Process Positive Regulation Of Cytoskeleton Organization Regulation Of Cell Adhesion Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Cell Division Mitotic Cell Cycle Process Positive Regulation Of Cell-cell Adhesion Protein Complex Assembly Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Calcium Ion Import Actin Filament Organization Regulation Of T Cell Activation Cytoskeleton Organization Positive Regulation Of Cell Activation Protein K63-linked Ubiquitination Protein Trimerization Cellular Protein Complex Assembly Positive Regulation Of Immune System Process Regulation Of Organelle Organization Regulation Of Microtubule-based Process Positive Regulation Of Neutrophil Differentiation Spliceosomal Complex Disassembly Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Regulation Of Actin Cytoskeleton Organization Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Positive Regulation Of Alpha-beta T Cell Differentiation Regulation Of Immune System Process Regulation Of Myeloid Cell Differentiation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Actin Filament Polymerization Positive Regulation Of Cellular Metabolic Process Regulation Of Lymphocyte Activation Negative Regulation Of ERBB Signaling Pathway Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Cellular Localization Cell Cycle Process Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length
Tagcloud ?		abcc5 cabpr cbr3 clonogenic comprehensive differentially dock8 dsc2 esophageal extracted fabp5 global gpx2 hence know microarray ndn nme oligonucleotide radiation radioresistant radiosensitive radiosensitivities radiosensitivity radiotherapy rpa1 skp1a spot te
Tagcloud (Difference) ?		abcc5 cabpr cbr3 clonogenic comprehensive differentially dock8 dsc2 esophageal extracted fabp5 global gpx2 hence know microarray ndn nme oligonucleotide radiation radioresistant radiosensitive radiosensitivities radiosensitivity radiotherapy rpa1 skp1a spot te
Tagcloud (Intersection) ?