LDOC1 and SUDS3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LDOC1	SUDS3
Description		LDOC1 regulator of NFKB signaling	SIN3A corepressor complex component SDS3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm Cytosol Nuclear Body Sin3-type Complex
	Molecular Function	Protein Binding	Histone Deacetylase Activity Protein Binding Enzyme Binding Histone Deacetylase Binding
	Biological Process	Maternal Placenta Development Negative Regulation Of Cell Population Proliferation Maternal Process Involved In Parturition Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Apoptotic Process Regulation Of Gene Expression Substantia Nigra Development Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of DNA-templated Transcription Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance
Pathways			HDACs deacetylate histones NoRC negatively regulates rRNA expression Ub-specific processing proteases Potential therapeutics for SARS
Drugs
Diseases
GWAS			Glucose homeostasis traits ( 25524916) Hemostatic factors and hematological phenotypes ( 22443383) Hippocampal sclerosis ( 25188341) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Morphine dose requirement in tonsillectomy and adenoidectomy surgery ( 24909733) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)
Interacting Genes		106 interacting genes: AATF ABLIM1 AEBP2 AIRIM AP1M1 AQP1 ATF4 ATP6V1G1 BARD1 BEX2 BYSL CCDC33 CCDC85B CDC5L CEBPE CFAP53 CTNNBL1 DPF2 DPPA4 ENKD1 FAM107A FAM110A FAM161A FAM193B FAM50B FAM90A1 FCHSD2 FOSL1 FXR2 GADD45GIP1 GNL3L GPANK1 HAUS1 HDAC4 HGS HOXB5 HOXC8 IKZF3 IKZF5 INPP1 IQCB1 JRK KRT15 KRT18 LATS1 LENG1 LMO2 LNX1 MBD3 MEAF6 MFAP1 MSGN1 MYC MZF1 NOD2 NRIP1 NXF1 PLEKHF2 POLL PPP1R18 PRPF18 PRPF31 PSMA1 PSMF1 RAB29 RALBP1 RASSF10 RIBC1 RNF6 RPP25 SCNM1 SDCBP SETD5 SH2D4A SMARCB1 SMARCD1 SUDS3 TASOR2 TBC1D7 TCEANC TEAD4 THAP7 TLE5 TMSB4XP1 TNNT1 TSGA10IP TSNAX TTC23 UBTFL1 UTP14A WDR25 WT1 ZBTB16 ZBTB24 ZFP1 ZGPAT ZNF124 ZNF250 ZNF408 ZNF564 ZNF587 ZNF629 ZNF648 ZNF688 ZNF774 ZNF835	7 interacting genes: BRMS1 CSNK2A1 GOLGA2 HDAC1 LDOC1 PTEN SRPK1
Entrez ID		23641	64426
HPRD ID		02322	12196
Ensembl ID		ENSG00000182195	ENSG00000111707
Uniprot IDs		O95751	Q9H7L9
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Nucleoplasm DNA-binding Transcription Factor Activity Nuclear Speck Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Stem Cell Population Maintenance Zinc Ion Binding Positive Regulation Of Stem Cell Population Maintenance DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Spindle Pole DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Transcription By RNA Polymerase II Chromatin NBAF Complex Positive Regulation Of RNA Biosynthetic Process Centrosome Positive Regulation Of DNA-templated Transcription Chromatin Organization Cytoskeleton Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Protein-DNA Complex Disassembly Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Remodeling Regulation Of Nucleotide-excision Repair Ribosome Biogenesis SWI/SNF Complex Positive Regulation Of Transcription By RNA Polymerase I Spliceosomal Complex	Sin3-type Complex Cell Death Programmed Cell Death Apoptotic Process Meiotic Spindle Organization Meiotic Spindle Assembly Negative Regulation Of Stem Cell Population Maintenance NF-kappaB Binding Rhythmic Process Membraneless Organelle Assembly Organelle Assembly Positive Regulation Of Stem Cell Population Maintenance Positive Regulation Of Protein Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Synaptic Vesicle Clustering Regulation Of Stem Cell Population Maintenance Negative Regulation Of Cell Motility Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Metabolic Process Spindle Assembly Enzyme Binding Krueppel-associated Box Domain Binding Negative Regulation Of Locomotion Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Collagen Type VI Trimer Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body PML Body Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Lysine Delactylase Activity Fungiform Papilla Formation Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Deoxyribonuclease Inhibitor Activity Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity Positive Regulation Of Protein Deacetylation Negative Regulation Of Phosphorylation Negative Regulation Of DNA Metabolic Process Positive Regulation Of Protein Glycosylation Histone Deacetylase Binding Protein Decrotonylase Activity Histone Decrotonylase Activity Circadian Rhythm Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Mitotic Spindle
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