DPPA4 and RPGRIP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DPPA4	RPGRIP1
Gene Name		developmental pluripotency associated 4	retinitis pigmentosa GTPase regulator interacting protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Axoneme Photoreceptor Connecting Cilium
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Lung-associated Mesenchyme Development	Visual Perception Eye Photoreceptor Cell Development Response To Stimulus Retina Development In Camera-type Eye
Pathways
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Corneal astigmatism ( 23761726)
Protein-Protein Interactions		17 interactors: BTBD2 CRK DPPA2 EIF4A2 EMD GRB2 HTT LDOC1 MAPK6 PTPRO QARS RPGRIP1 RPS6KB1 SH3GL1 SH3GL2 SH3GL3 VIM	24 interactors: AEN BRCA1 CBX8 CCDC146 CHCHD3 CSPP1 DPPA4 FAM74A4 FEM1C GATAD2B HEYL IQCE MAGEB2 NPHP4 PTF1A RPGR RPP25L SCNM1 TBC1D7 TFPT TRIB3 ZNF337 ZNF417 ZNF564
Entrez ID		55211	57096
HPRD ID		16836	05673
Ensembl ID		ENSG00000121570	ENSG00000092200
Uniprot IDs		Q7L190	Q96KN7
PDB IDs
Enriched GO Terms of Interacting Partners?		Nervous System Development Anatomical Structure Development Cell Development System Development Response To Organic Substance Cellular Response To Organic Substance Cellular Response To Stimulus Developmental Process Enzyme Linked Receptor Protein Signaling Pathway Response To Stimulus Central Nervous System Development Cellular Response To Growth Factor Stimulus Multicellular Organismal Development Response To Growth Factor Endocytosis Tissue Development Signal Transduction Cell Differentiation Insulin Receptor Signaling Pathway Signaling Cell Communication Cellular Response To Organonitrogen Compound Vesicle-mediated Transport Regulation Of Cell Proliferation Movement Of Cell Or Subcellular Component Regulation Of Cellular Process Negative Regulation Of Neuron Differentiation Response To Hormone Organ Development Neuron Development Generation Of Neurons Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Muscle Contraction Cell Surface Receptor Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neurogenesis Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Signal Transduction Neuron Differentiation Muscle System Process Neural Plate Formation Glutaminyl-tRNA Aminoacylation Negative Regulation Of RNA-directed RNA Polymerase Activity Slit Diaphragm Assembly Regulation Of Translation Negative Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Cell Proliferation	Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Fatty Acid Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Apoptotic Signaling Pathway Negative Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination Negative Regulation Of Lipid Biosynthetic Process Photoreceptor Cell Development Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Androgen Receptor Activity Negative Regulation Of Lipid Metabolic Process Regulation Of Fatty Acid Metabolic Process Regulation Of Cellular Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Neural Retina Development Negative Regulation Of Cilium Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Eye Development Signal Transduction By P53 Class Mediator Amacrine Cell Differentiation Cellular Response To Indole-3-methanol
Tagcloud ?		assembled binds biochemical chromatin developmental digestion dynamics embryonic es frap h1 h3 histone immunoprecipitation implies micrococcal mnase mobility modulates nuclease nuclei photobleaching pluripotency poorly proper recovery truncated uncharacterized understood	ahi1 bardet biedl c2cd3 cc2d2a cc2d2b ccdc135 cep76 cilia ciliogenesis ciliopathies dyneins gruber jbts jouberin joubert meckel midasins mks mks6 moxr nephronophthisis nphp nphp1 nphp4 tgl throw ttl
Tagcloud (Difference) ?		assembled binds biochemical chromatin developmental digestion dynamics embryonic es frap h1 h3 histone immunoprecipitation implies micrococcal mnase mobility modulates nuclease nuclei photobleaching pluripotency poorly proper recovery truncated uncharacterized understood	ahi1 bardet biedl c2cd3 cc2d2a cc2d2b ccdc135 cep76 cilia ciliogenesis ciliopathies dyneins gruber jbts jouberin joubert meckel midasins mks mks6 moxr nephronophthisis nphp nphp1 nphp4 tgl throw ttl
Tagcloud (Intersection) ?