LDOC1 and MEAF6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		LDOC1	MEAF6
Description		LDOC1 regulator of NFKB signaling	MYST/Esa1 associated factor 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Histone Acetyltransferase Complex Chromosome, Centromeric Region Kinetochore Nucleosome Nucleus Nucleoplasm Chromosome Nucleolus NuA4 Histone Acetyltransferase Complex MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Protein Binding	Protein Binding Histone H3K14 Acetyltransferase Activity Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity
	Biological Process	Maternal Placenta Development Negative Regulation Of Cell Population Proliferation Maternal Process Involved In Parturition Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide	Regulation Of Cell Growth Regulation Of DNA Replication Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Regulation Of Developmental Process Regulation Of Cell Cycle Regulation Of Hemopoiesis Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of DNA Biosynthetic Process Regulation Of Double-strand Break Repair
Pathways			HATs acetylate histones HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS			Eyebrow thickness ( 26926045)
Interacting Genes		106 interacting genes: AATF ABLIM1 AEBP2 AIRIM AP1M1 AQP1 ATF4 ATP6V1G1 BARD1 BEX2 BYSL CCDC33 CCDC85B CDC5L CEBPE CFAP53 CTNNBL1 DPF2 DPPA4 ENKD1 FAM107A FAM110A FAM161A FAM193B FAM50B FAM90A1 FCHSD2 FOSL1 FXR2 GADD45GIP1 GNL3L GPANK1 HAUS1 HDAC4 HGS HOXB5 HOXC8 IKZF3 IKZF5 INPP1 IQCB1 JRK KRT15 KRT18 LATS1 LENG1 LMO2 LNX1 MBD3 MEAF6 MFAP1 MSGN1 MYC MZF1 NOD2 NRIP1 NXF1 PLEKHF2 POLL PPP1R18 PRPF18 PRPF31 PSMA1 PSMF1 RAB29 RALBP1 RASSF10 RIBC1 RNF6 RPP25 SCNM1 SDCBP SETD5 SH2D4A SMARCB1 SMARCD1 SUDS3 TASOR2 TBC1D7 TCEANC TEAD4 THAP7 TLE5 TMSB4XP1 TNNT1 TSGA10IP TSNAX TTC23 UBTFL1 UTP14A WDR25 WT1 ZBTB16 ZBTB24 ZFP1 ZGPAT ZNF124 ZNF250 ZNF408 ZNF564 ZNF587 ZNF629 ZNF648 ZNF688 ZNF774 ZNF835	8 interacting genes: CATSPERT CCDC85B FXR2 L3MBTL2 LDOC1 MRGBP PLEKHF2 TRIM54
Entrez ID		23641	64769
HPRD ID		02322	13347
Ensembl ID		ENSG00000182195	ENSG00000163875
Uniprot IDs		O95751	Q9HAF1
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Nucleoplasm DNA-binding Transcription Factor Activity Nuclear Speck Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Stem Cell Population Maintenance Zinc Ion Binding Positive Regulation Of Stem Cell Population Maintenance DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Spindle Pole DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Transcription By RNA Polymerase II Chromatin NBAF Complex Positive Regulation Of RNA Biosynthetic Process Centrosome Positive Regulation Of DNA-templated Transcription Chromatin Organization Cytoskeleton Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Protein-DNA Complex Disassembly Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Remodeling Regulation Of Nucleotide-excision Repair Ribosome Biogenesis SWI/SNF Complex Positive Regulation Of Transcription By RNA Polymerase I Spliceosomal Complex
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