DPPA4 and BTBD2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		DPPA4	BTBD2
Gene Name		developmental pluripotency associated 4	BTB (POZ) domain containing 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytoplasmic MRNA Processing Body
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Lung-associated Mesenchyme Development
Pathways
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Corneal astigmatism ( 23761726)
Protein-Protein Interactions		17 interactors: BTBD2 CRK DPPA2 EIF4A2 EMD GRB2 HTT LDOC1 MAPK6 PTPRO QARS RPGRIP1 RPS6KB1 SH3GL1 SH3GL2 SH3GL3 VIM	26 interactors: BRD7 C14orf1 CCDC90B CDK2 COPS6 CRMP1 DPPA4 EEF1A1 GAPDH GBP2 GDF9 IGSF21 KPNA2 PTN RBM48 SETDB1 SMAD1 SMAD2 TGFBR1 TLE1 TOP1 TP53 TRIM5 UBR1 UNC119 ZNF512B
Entrez ID		55211	55643
HPRD ID		16836	12252
Ensembl ID		ENSG00000121570	ENSG00000133243
Uniprot IDs		Q7L190	Q9BX70
PDB IDs			3NO8
Enriched GO Terms of Interacting Partners?		Nervous System Development Anatomical Structure Development Cell Development System Development Response To Organic Substance Cellular Response To Organic Substance Cellular Response To Stimulus Developmental Process Enzyme Linked Receptor Protein Signaling Pathway Response To Stimulus Central Nervous System Development Cellular Response To Growth Factor Stimulus Multicellular Organismal Development Response To Growth Factor Endocytosis Tissue Development Signal Transduction Cell Differentiation Insulin Receptor Signaling Pathway Signaling Cell Communication Cellular Response To Organonitrogen Compound Vesicle-mediated Transport Regulation Of Cell Proliferation Movement Of Cell Or Subcellular Component Regulation Of Cellular Process Negative Regulation Of Neuron Differentiation Response To Hormone Organ Development Neuron Development Generation Of Neurons Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Muscle Contraction Cell Surface Receptor Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neurogenesis Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Signal Transduction Neuron Differentiation Muscle System Process Neural Plate Formation Glutaminyl-tRNA Aminoacylation Negative Regulation Of RNA-directed RNA Polymerase Activity Slit Diaphragm Assembly Regulation Of Translation Negative Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Cell Proliferation	Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Organic Substance Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Response To Organic Substance Primary MiRNA Processing Cellular Response To Growth Factor Stimulus Response To Growth Factor Response To Stimulus Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Proliferation Regulation Of RNA Metabolic Process Cell Surface Receptor Signaling Pathway SMAD Protein Complex Assembly Nucleobase-containing Compound Metabolic Process Growth Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Biosynthetic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Viral Process Cell Fate Commitment Transcription, DNA-templated Negative Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Production Of MiRNAs Involved In Gene Silencing By MiRNA Response To Cholesterol Macromolecule Biosynthetic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Signal Transduction Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Proliferation Positive Regulation Of Cellular Metabolic Process Cellular Response To Interferon-gamma Activin Receptor Signaling Pathway
Tagcloud ?		assembled binds biochemical chromatin developmental digestion dynamics embryonic es frap h1 h3 histone immunoprecipitation implies micrococcal mnase mobility modulates nuclease nuclei photobleaching pluripotency poorly proper recovery truncated uncharacterized understood
Tagcloud (Difference) ?		assembled binds biochemical chromatin developmental digestion dynamics embryonic es frap h1 h3 histone immunoprecipitation implies micrococcal mnase mobility modulates nuclease nuclei photobleaching pluripotency poorly proper recovery truncated uncharacterized understood
Tagcloud (Intersection) ?