PPP2CA and PXN

  • Number of citations of the paper that reports this interaction (PMID 10675325)
  • 37
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

PPP2CA

PXN

Gene Name protein phosphatase 2, catalytic subunit, alpha isozyme paxillin
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 71 interactors: ADCY8 AKT1 APC AXIN1 BCL2 BEST1 BMPR1B CAD CAV1 CCNG1 CCNG2 CDK2 CDK6 CDKN2C CHEK2 CXCR2 DVL3 EEF2 EIF4EBP1 ETF1 FCAR GABRB3 GAD1 GOLGA2 HTT IGBP1 ISYNA1 JAK2 MAPK1 MAPK3 MAPT MID1 MRPS26 MYH9 NME2 NXN PACS1 PPP1CA PPP2R1A PPP2R1B PPP2R2A PPP2R3A PPP2R3B PPP2R5B PPP2R5C PPP2R5E PRKAA1 PRKCD PTN PXN RACGAP1 RBL2 RELA RHO RHOB RPS6KB1 RRAS SET SGK1 SGOL1 SGOL2 STAT5A STAT5B STRN TLX1 TP53 TRIP13 TSC2 VAC14 VDR XRN1 73 interactors: ABL1 AHCY AR ARHGEF7 ASAP1 ASAP2 BCAR1 BCL2 CASP3 CEACAM1 CLTC CREB3L2 CRK CRKL CSK DGUOK EPHB1 FYN GART GIT1 GIT2 GRB2 GSK3A GSK3B GSN HDAC6 ILK ITGA4 ITGA6 ITGA9 ITGB1 ITGB3 LCK LIMK1 MAPK1 MAPK3 MAPK8 MATK NCK1 NEDD9 NF2 PABPC1 PAK1 PAK3 PARVA PDPK1 PKD1 POLR1D PPP2CA PPP2R5C PTEN PTK2 PTK2B PTPN11 PTPN12 PTPRH RASA1 REPS2 RNF5 SDC4 SELE SORBS1 SRC SYK TLN1 TRIP6 TUBA1B TUBA3C TUBA8 TUBG1 TUBG2 VCL XPO1
Entrez ID 5515 5829
HPRD ID 08912 03937
Ensembl ID ENSG00000089159
Uniprot IDs B3KUN1 P67775 E7EMK8 F5GZ78 P49023
PDB IDs 2IAE 2IE3 2IE4 2NPP 2NYL 2NYM 3C5W 3DW8 3FGA 3K7V 3K7W 3P71 4I5L 4I5N 4IYP 1KKY 1KL0 1OW6 1OW7 1OW8 2K2R 2O9V 2VZD 2VZG 2VZI 3GM1 3PY7 3RQE 3RQF 3RQG 3U3C 3U3F 4EDN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
bioinformatics  bmp2  calm1  cnaq  csf2rb  csf3  expressions  fifteen  gria2  il10ra  il10rb  il11ra  il3ra  il6st  lifr  lymphatic  microarrays  myl9  mylk  myosin  nonsmokers  nsclc  paraneoplastic  pathohistological  plcb4  rac3  rock2  thbs1  verify 
acclimatized  adra1d  altitude  araf  argef11  arhgap24  ascent  cardiogenic  circuitry  cldn23  cldn6  ece1  ednra  genic  hape  inciting  map2k2  map2k7  mapk10  mylk  oxphos  pak3  pathoetiology  plcb1  skew  sos1  unacclimatized  vasoconstriction  vcam1 
Tagcloud (Difference) ?
bioinformatics  bmp2  calm1  cnaq  csf2rb  csf3  expressions  fifteen  gria2  il10ra  il10rb  il11ra  il3ra  il6st  lifr  lymphatic  microarrays  myl9  myosin  nonsmokers  nsclc  paraneoplastic  pathohistological  plcb4  rac3  rock2  thbs1  verify 
acclimatized  adra1d  altitude  araf  argef11  arhgap24  ascent  cardiogenic  circuitry  cldn23  cldn6  ece1  ednra  genic  hape  inciting  map2k2  map2k7  mapk10  oxphos  pak3  pathoetiology  plcb1  skew  sos1  unacclimatized  vasoconstriction  vcam1 
Tagcloud (Intersection) ?
mylk