SLC41A3 and PDZD3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SLC41A3	PDZD3
Gene Name		solute carrier family 41, member 3	PDZ domain containing 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Cytosol Brush Border Subapical Complex Apical Part Of Cell
	Molecular Function	Cation Transmembrane Transporter Activity	Protein Binding Protein C-terminus Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity
	Biological Process	Cation Transmembrane Transport	Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance CGMP-mediated Signaling Negative Regulation Of CGMP Biosynthetic Process Negative Regulation Of Guanylate Cyclase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: APP MAPK6 PDZD3 REL	17 interactors: ABCC2 ASAP3 CACNA1S CFTR GUCY2C PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7
Entrez ID		54946	79849
HPRD ID		11580	06191
Ensembl ID		ENSG00000114544	ENSG00000172367
Uniprot IDs		D3DNA7 Q96GZ6	B0YJ61 Q86UT5
PDB IDs			2V90
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Guanylate Cyclase Activity Negative Regulation Of CGMP Biosynthetic Process Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling CGMP-mediated Signaling Receptor Guanylyl Cyclase Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Interleukin-12 Biosynthetic Process Signal Transduction Negative Regulation Of Cellular Metabolic Process Regulation Of Interleukin-12 Biosynthetic Process Cellular Copper Ion Homeostasis Signaling Cell Communication Regulation Of CGMP Biosynthetic Process Copper Ion Homeostasis Suckling Behavior Negative Regulation Of Lyase Activity Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Cyclic-nucleotide-mediated Signaling Regulation Of CGMP Metabolic Process Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Response To Stimulus RNA Polyadenylation Neuron Recognition Negative Regulation Of Catalytic Activity Negative Regulation Of Nucleotide Metabolic Process Innate Immune Response Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway NIK/NF-kappaB Signaling Water Transport Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Interleukin-12 Production Regulation Of G2/M Transition Of Mitotic Cell Cycle Fluid Transport Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition I-kappaB Kinase/NF-kappaB Signaling	Transmembrane Transport Ion Transport Ion Transmembrane Transport Sodium-independent Organic Anion Transport Anion Transport Organic Anion Transport Anion Transmembrane Transport Drug Transport Monocarboxylic Acid Transport Quaternary Ammonium Group Transport Transport Cation Transmembrane Transport Drug Transmembrane Transport Carboxylic Acid Transport Organic Acid Transport Antibiotic Transport Toxin Transport Ammonium Transmembrane Transport Organic Cation Transport Cation Transport Oligopeptide Transport Ammonium Transport Response To Drug Inorganic Anion Transport Carnitine Transmembrane Transport Carnitine Transport Lipid Transport Lipid Localization Monovalent Inorganic Cation Transport Dipeptide Transport Histamine Uptake Positive Regulation Of ARF GTPase Activity Short-chain Fatty Acid Import Positive Regulation Of Voltage-gated Chloride Channel Activity Positive Regulation Of Intestinal Epithelial Structure Maintenance Quorum Sensing Involved In Interaction With Host Sodium-dependent Organic Cation Transport Fatty Acid Transport Regulation Of Intestinal Epithelial Structure Maintenance Prostaglandin Transport Peptide Transport Hormone Transport Extraocular Skeletal Muscle Development Oligopeptide Transmembrane Transport Regulation Of Chloride Transport Amide Transport Iodide Transport Thyroid Hormone Transport Transepithelial Chloride Transport Cellular Chloride Ion Homeostasis
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