SLC41A3 and NHERF4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SLC41A3	NHERF4
Description		solute carrier family 41 member 3	NHERF family PDZ scaffold protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Membrane	Cytoplasm Cytosol Plasma Membrane Brush Border Membrane Apical Plasma Membrane Apical Junction Complex Apical Part Of Cell
	Molecular Function	Protein Binding Monoatomic Cation Transmembrane Transporter Activity Magnesium Ion Transmembrane Transporter Activity Magnesium:sodium Antiporter Activity	Signaling Receptor Binding Protein Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity Protein-membrane Adaptor Activity Ubiquitin-specific Protease Binding
	Biological Process	Monoatomic Ion Transport Monoatomic Cation Transport Sodium Ion Transmembrane Transport Mitochondrial Magnesium Ion Transmembrane Transport	Monoatomic Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance Negative Regulation Of CGMP-mediated Signaling Protein Localization To Plasma Membrane
Pathways			Intestinal infectious diseases
Drugs
Diseases
GWAS		Bell's palsy ( 33602968)
Interacting Genes		17 interacting genes: APP ARLN CCL3L3 CCR2 CREB3 GPR37 IGFBP5 MAPK6 NHERF4 NPSR1 PLP1 REL SMCO4 SMO SUFU TMBIM6 TSPO2	18 interacting genes: ABCC2 ASAP3 CACNA1S CFTR GUCY2C PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7 TAS2R8
Entrez ID		54946	79849
HPRD ID		11580	06191
Ensembl ID		ENSG00000114544	ENSG00000172367
Uniprot IDs		Q96GZ6	B0YJ61 E9PPZ1 Q86UT5
PDB IDs			2V90
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Monocyte Chemotaxis Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Monocyte Chemotaxis Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Signal Transduction Positive Regulation Of Locomotion Locomotion Regulation Of Signal Transduction Spinal Cord Dorsal/ventral Patterning Regulation Of Calcium Ion Transport G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Mononuclear Cell Migration Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Leukocyte Chemotaxis Astrocyte Activation Neuropeptide Receptor Activity Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Migration Chemotaxis Regulation Of Metal Ion Transport Regulation Of Cell Motility Regulation Of Intracellular Signal Transduction Regulation Of Calcium Ion Transmembrane Transport Regulation Of Locomotion Positive Regulation Of Chemotaxis Regulation Of Mononuclear Cell Migration Endoplasmic Reticulum Positive Regulation Of Leukocyte Migration G Protein-coupled Receptor Activity Hair Follicle Morphogenesis Regulation Of Protein Localization To Nucleus Regulation Of Transport Amyloid-beta Complex Growth Cone Lamellipodium Intracellular Signal Transduction Regulation Of Monoatomic Ion Transport Regulation Of Response To Calcium Ion Positive Regulation Of Cell Communication Dendrite Amylin Binding Positive Regulation Of Signaling Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Toll Signaling Pathway Positive Regulation Of T Cell Migration Positive Regulation Of Signal Transduction Dendrite Development	Organic Anion Transmembrane Transporter Activity Transmembrane Transporter Activity Transmembrane Transport Monoatomic Ion Transport Apical Plasma Membrane Sodium-independent Organic Anion Transport Sodium-independent Organic Anion Transmembrane Transporter Activity Transport Across Blood-brain Barrier Xenobiotic Transport Organic Anion Transport Monocarboxylic Acid Transport Carboxylic Acid Transport Organic Acid Transport Basal Plasma Membrane Quaternary Ammonium Group Transmembrane Transporter Activity Plasma Membrane Organic Hydroxy Compound Transport Organic Cation Transmembrane Transporter Activity Basolateral Plasma Membrane Quaternary Ammonium Group Transport Xenobiotic Export From Cell Vascular Process In Circulatory System Lipid Transport Tripeptide Transmembrane Transporter Activity Tripeptide Import Across Plasma Membrane Oligopeptide Transmembrane Transporter Activity Circulatory System Process Membrane Bile Acid And Bile Salt Transport Organic Cation Transport Amino-acid Betaine Transmembrane Transporter Activity Symporter Activity Dipeptide Transmembrane Transporter Activity Peptide:proton Symporter Activity Carnitine Transmembrane Transporter Activity Dipeptide Transport Dipeptide Import Across Plasma Membrane Dipeptide Transmembrane Transport Import Across Plasma Membrane Carnitine Transport Carnitine Transmembrane Transport Bile Acid Transmembrane Transporter Activity ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Import Into Cell Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Amino-acid Betaine Transport Serotonin Transport PDZ Domain Binding Oligopeptide Transmembrane Transport Oligopeptide Transport
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