ATG9A and KRTAP8-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATG9A	KRTAP8-1
Description		autophagy related 9A	keratin associated protein 8-1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Phagophore Assembly Site Autophagosome Membrane Cytoplasm Mitochondrion Endosome Late Endosome Autophagosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Membrane Cytoplasmic Vesicle Late Endosome Membrane Mitochondrial Membrane Phagophore Assembly Site Membrane Recycling Endosome Recycling Endosome Membrane Synaptic Membrane	Cytosol Intermediate Filament
	Molecular Function	Protein Binding Phospholipid Scramblase Activity	Protein Binding
	Biological Process	Autophagosome Assembly Mitophagy Lipid Transport Autophagy Negative Regulation Of Macrophage Cytokine Production Plasma Membrane Phospholipid Scrambling Negative Regulation Of Interferon-beta Production Protein Localization To Golgi Apparatus Protein Localization To Phagophore Assembly Site Piecemeal Microautophagy Of The Nucleus Innate Immune Response Bone Morphogenesis Reticulophagy Programmed Necrotic Cell Death
Pathways		Macroautophagy PINK1-PRKN Mediated Mitophagy	Keratinization
Drugs
Diseases
GWAS			Gut microbiota (bacterial taxa) ( 27723756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		48 interacting genes: ADAMTSL4 ANKRD10 AP2M1 CERCAM CFAP68 CIB4 CYSRT1 ETHE1 HDHD3 KLHL20 KPRP KRT31 KRT33B KRT34 KRT35 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP11-1 KRTAP13-3 KRTAP19-1 KRTAP3-2 KRTAP3-3 KRTAP4-2 KRTAP5-9 KRTAP6-2 KRTAP8-1 KRTAP9-2 LONRF1 MAPK6 MEOX1 MEOX2 MGAT5B NBPF19 NDUFB7 NOTCH2NLA OXER1 REL SRC SRCAP TBK1 TCF4 TRIM42 UBE3A YPEL3 ZBTB42 ZNF581 ZNF620	78 interacting genes: AANAT AGXT AOC1 ARID5A ATG9A ATXN1L BANP BCAS2 BHLHE40 C11orf16 C1orf94 CAMK2A CCDC17 CCNK CDA CERCAM CIMIP1 CREB5 CRYAB CYSRT1 DAB1 DAZAP2 DMRTB1 DTX2 FAAP20 FAM168A FAM83A FOXD2 FOXP3 GATA2 GCM2 GLIS2 HEY2 HOXC8 HYPK KRTAP12-4 KRTAP19-5 KRTAP26-1 MKRN3 MYOZ3 NKX2-5 NOXA1 P4HA3 PAX3 PITX1 PLSCR4 POGZ POU6F2 PROP1 PRR13 PRR35 PSMA3 RAMAC RBPMS RBPMS2 RNF38 RUSC1 SAXO4 SLC68A1 SMR3A SMUG1 SNRPC TBX18 TEKT3 TIAL1 TLE5 TLX3 TMSB4X TNIP1 TNPO2 TSPYL6 VENTX VEZF1 YTHDF1 ZBTB32 ZC3H10 ZIC1 ZNF34
Entrez ID		79065	337879
HPRD ID		07979	11221
Ensembl ID		ENSG00000198925	ENSG00000183640
Uniprot IDs		Q7Z3C6	Q8IUC2
PDB IDs		6WQZ 6WR4 7JLO 7JLP 7JLQ 8KBZ 8KC3 8Y1L
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Structural Molecule Activity Epidermis Development Intermediate Filament Organization Somite Specification Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process	Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Nucleus Chromatin DNA Binding Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Sequence-specific DNA Binding Cytoplasmic Stress Granule Protein Homodimerization Activity Identical Protein Binding Regulation Of Gene Expression Nucleoplasm Regulation Of Primary Metabolic Process Cell Fate Commitment Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Negative Regulation Of Muscle Cell Differentiation Pituitary Gland Development Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Cardiac Muscle Cell Fate Commitment Central Nervous System Development Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Cardiac Muscle Cell Development Ventricular Cardiac Muscle Cell Development Cardiac Cell Development
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