PLP2 and SHBG

Number of citations of the paper that reports this interaction (PMID 15862967)
1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLP2	SHBG
Gene Name		proteolipid protein 2 (colonic epithelium-enriched)	sex hormone-binding globulin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Extracellular Region Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Ion Transmembrane Transporter Activity Chemokine Binding	Androgen Binding
	Biological Process	Ion Transport Chemotaxis Cytokine-mediated Signaling Pathway Ion Transmembrane Transport	Primary Spermatocyte Growth
Pathways
Drugs
Diseases
GWAS			Androgen levels ( 22936694) Protein quantitative trait loci ( 18464913) Sex hormone-binding globulin levels ( 22675492 22829776) Testosterone levels ( 21998597)
Protein-Protein Interactions		9 interactors: BCAP31 CCDC155 CCR1 CLN8 DLGAP4 IKBKAP SHBG TMEM79 VKORC1	62 interactors: A2M ACPP ACTA2 ACTB ACTG2 AK2 AKR1B1 AP1B1 AP2A1 APEH APOBEC3C APOD ASB16-AS1 ATP5A1 AZGP1 C9orf24 CD177 CECR5 CEP192 CLDN4 CLEC4G COL1A2 CTSD DDX3Y DES DSTN EEF1A1 EIF3E EIF3F FLNA FLOT1 FYTTD1 GRB2 HYI JMJD7-PLA2G4B KLK4 MPDU1 MT1F MT1G MT2A MXD4 NOMO1 PACSIN2 PKM PLA2G4A PLP2 PSTPIP1 PSTPIP2 PTGDS RMND5B SEMA3F SLC37A1 SLC37A4 SNAPIN SNRNP70 SORD SRF SRI TINAGL1 UBE2O UBE3A ZC3H12A
Entrez ID		5355	6462
HPRD ID		02121	01646
Ensembl ID		ENSG00000102007	ENSG00000129214
Uniprot IDs		Q04941	B0FWH2 B4DYU0 I3L1J1 I3L2X4 P04278
PDB IDs			1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV 1LHW
Enriched GO Terms of Interacting Partners?		Chromosome Localization To Nuclear Envelope Involved In Synapsis Primary Spermatocyte Growth Spermatogenesis Male Gamete Generation L-glutamate Uptake Involved In Synaptic Transmission Homeostatic Process Cuticle Development Gamete Generation Cornification Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Age-dependent Response To Oxidative Stress Protein Localization To Endoplasmic Reticulum Exit Site Vitamin K Metabolic Process Sexual Reproduction Multicellular Organismal Reproductive Process Somatic Motor Neuron Differentiation Multicellular Organism Reproduction L-glutamate Import Chemical Homeostasis Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of Monocyte Chemotaxis Establishment Of Localization In Cell Neurotransmitter Uptake Calcium-mediated Signaling Using Intracellular Calcium Source Peptidyl-glutamic Acid Carboxylation Cellular Calcium Ion Homeostasis Regulation Of Monocyte Chemotaxis Dendritic Cell Chemotaxis Neurofilament Cytoskeleton Organization Reproduction Calcium Ion Homeostasis Neuromuscular Process Controlling Posture Amino Acid Import Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Mitochondrial Calcium Ion Homeostasis Establishment Of Skin Barrier Exocytosis Positive Regulation Of Cellular Component Movement	Platelet Activation Extracellular Matrix Disassembly Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Cellular Response To Zinc Ion Endocytosis Vesicle-mediated Transport Response To Wounding Transport Endosomal Transport Cell Activation Response To Zinc Ion Cell Projection Organization Immune System Process MRNA Transcription From RNA Polymerase II Promoter Glucose Metabolic Process MRNA Transcription Neuron Projection Development Movement Of Cell Or Subcellular Component Cellular Response To Cadmium Ion Regulation Of Water Loss Via Skin Formation Of Translation Preinitiation Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cell Morphogenesis Involved In Differentiation Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Receptor-mediated Endocytosis Hexose Metabolic Process Neuron Development Extracellular Matrix Organization Viral Process Cytoplasmic Sequestering Of Protein Regulation Of Defense Response To Virus By Virus Extracellular Structure Organization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Axon Development Antigen Processing And Presentation Of Peptide Antigen Locomotion Negative Regulation Of Growth Monosaccharide Metabolic Process Sperm Entry Negative Regulation Of T Cell Migration Contractile Actin Filament Bundle Assembly Negative Regulation Of Lipoprotein Lipid Oxidation Positive Regulation Of Late Endosome To Lysosome Transport Sorbitol Catabolic Process L-xylitol Metabolic Process L-xylitol Catabolic Process Fructose Biosynthetic Process
Tagcloud ?		antiviral bona coronavirus coronaviruses deubiquitinates engages ensure escape fide hcov ifnbeta immunopathology innate interferon irf7 mdm2 meanwhile nl63 nonstructural oncoprotein papain plps proteases proteasomal rampant reveals stabilizes suppressors usually	asgr assigned chr distances f1 grin grin1 grin2a grin2b grin2c grin2d grm grm1 grm2 grm3 grm4 grm5 grm6 linkage maps metabotropic mmyhse myhse ppy rr24 shr symbol wtc zi
Tagcloud (Difference) ?		antiviral bona coronavirus coronaviruses deubiquitinates engages ensure escape fide hcov ifnbeta immunopathology innate interferon irf7 mdm2 meanwhile nl63 nonstructural oncoprotein papain plps proteases proteasomal rampant reveals stabilizes suppressors usually	asgr assigned chr distances f1 grin grin1 grin2a grin2b grin2c grin2d grm grm1 grm2 grm3 grm4 grm5 grm6 linkage maps metabotropic mmyhse myhse ppy rr24 shr symbol wtc zi
Tagcloud (Intersection) ?