PLP2 and AQP8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLP2	AQP8
Description		proteolipid protein 2	aquaporin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane	Mitochondrion Mitochondrial Inner Membrane Endoplasmic Reticulum Smooth Endoplasmic Reticulum Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Smooth Endoplasmic Reticulum Membrane Brush Border Membrane Mitochondrial Membrane Apical Part Of Cell Intracellular Canaliculus Intracellular Vesicle
	Molecular Function	Protein Binding Monoatomic Ion Transmembrane Transporter Activity Chemokine Binding	Protein Binding Ammonium Channel Activity Water Channel Activity Methylammonium Channel Activity Urea Channel Activity Channel Activity
	Biological Process	Monoatomic Ion Transport Chemotaxis Cytokine-mediated Signaling Pathway Monoatomic Ion Transmembrane Transport	Water Transport Urea Transport Methylammonium Transport One-carbon Compound Transport B Cell Differentiation Transepithelial Water Transport Regulation Of Cholesterol Biosynthetic Process Transmembrane Transport Cellular Response To CAMP Urea Transmembrane Transport Ammonium Transmembrane Transport Methylammonium Transmembrane Transport Hydrogen Peroxide Transmembrane Transport Ammonium Import Across Plasma Membrane Cellular Detoxification
Pathways			Detoxification of Reactive Oxygen Species Passive transport by Aquaporins Developmental Lineage of Pancreatic Acinar Cells
Drugs
Diseases
GWAS		Platelet distribution width ( 32888494)	Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 27400856)
Interacting Genes		79 interacting genes: AQP2 AQP3 AQP6 AQP8 ARFIP2 ARL13B ASGR2 ATP5PF BCAP31 BIK BNIP3 CCR1 CD53 CD79A CERS4 CIAO2A CLDN5 CLN8 CPLX4 CRB3 CREB3L1 CYB561 CYBC1 CYBRD1 DARS2 DLGAP4 DNAJC1 EBP ELOVL5 ELP1 EVI2A FAM209A FAM210B FATE1 FCER1G FKBP7 FNDC9 GPR151 GPX8 HSBP1L1 HSD17B11 HSD17B13 KASH5 LHFPL1 LHFPL5 LMNA LRRC4C MGST3 MUC1 NDRG4 PACC1 PDZK1IP1 PIGP PSCA PTGES PVR REEP4 RETREG3 RNF5 SAR1A SCN3B SGPL1 SHBG SLC10A6 SLC14A2 SLC18A1 SLC2A13 SLC35H1 SPG21 SPN THAP4 TM4SF19 TMEM14B TMEM31 TMEM51 TMEM79 TMPRSS2 TMX2 VKORC1	6 interacting genes: CYBC1 PLP2 PLPP6 SERP1 STX12 TMEM120B
Entrez ID		5355	343
HPRD ID		02121	04778
Ensembl ID		ENSG00000102007	ENSG00000103375
Uniprot IDs		Q04941	O94778
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding Water Channel Activity Water Transport Renal Water Transport One-carbon Compound Transport Urea Transmembrane Transport Urea Transport Fluid Transport PH-gated Chloride Channel Activity Mitochondrial Membrane Channel Activity Apical Plasma Membrane Ascorbate Homeostasis Steroid Dehydrogenase Activity Organic Hydroxy Compound Transport Endoplasmic Reticulum-autophagosome Adaptor Activity Transmembrane Monodehydroascorbate Reductase Activity Glutathione Peroxidase Activity Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Transmembrane Transport Urea Transmembrane Transporter Activity Identical Protein Binding Glycerol Transmembrane Transport Plasma Membrane Substrate Localization To Autophagosome Ammonium Channel Activity Polyol Transmembrane Transport	Endoplasmic Reticulum Membrane Nuclear Inner Membrane Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Endoplasmic Reticulum Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation Chemokine Binding Postsynaptic Recycling Endosome Muscle Organ Morphogenesis Positive Regulation Of Growth Hormone Secretion Respiratory Burst Involved In Defense Response Respiratory Burst After Phagocytosis Lipid Phosphatase Activity Farnesyl Diphosphate Metabolic Process Sphingosine-1-phosphate Phosphatase Activity Protein Prenylation Lysophosphatidic Acid Phosphatase Activity Regulation Of Neutrophil Activation Monoatomic Ion Transmembrane Transporter Activity Membrane Regulation Of Growth Hormone Secretion Phosphatidate Phosphatase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?