SHBG and AZGP1

Number of citations of the paper that reports this interaction (PMID 15862967)
1

Data Source:
BioGRID (two hybrid)

		SHBG	AZGP1
Gene Name		sex hormone-binding globulin	alpha-2-glycoprotein 1, zinc-binding
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Vesicular Exosome	Extracellular Region Extracellular Space Nucleus Plasma Membrane MHC Class I Protein Complex Extracellular Vesicular Exosome
	Molecular Function	Androgen Binding	Glycoprotein Binding Antigen Binding Ribonuclease Activity Protein Transmembrane Transporter Activity Peptide Antigen Binding
	Biological Process	Primary Spermatocyte Growth	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Retina Homeostasis Positive Regulation Of T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Immune Response Cell Adhesion Negative Regulation Of Cell Proliferation Antigen Processing And Presentation Protein Transmembrane Transport RNA Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS		Androgen levels ( 22936694) Protein quantitative trait loci ( 18464913) Sex hormone-binding globulin levels ( 22675492 22829776) Testosterone levels ( 21998597)
Protein-Protein Interactions		62 interactors: A2M ACPP ACTA2 ACTB ACTG2 AK2 AKR1B1 AP1B1 AP2A1 APEH APOBEC3C APOD ASB16-AS1 ATP5A1 AZGP1 C9orf24 CD177 CECR5 CEP192 CLDN4 CLEC4G COL1A2 CTSD DDX3Y DES DSTN EEF1A1 EIF3E EIF3F FLNA FLOT1 FYTTD1 GRB2 HYI JMJD7-PLA2G4B KLK4 MPDU1 MT1F MT1G MT2A MXD4 NOMO1 PACSIN2 PKM PLA2G4A PLP2 PSTPIP1 PSTPIP2 PTGDS RMND5B SEMA3F SLC37A1 SLC37A4 SNAPIN SNRNP70 SORD SRF SRI TINAGL1 UBE2O UBE3A ZC3H12A	4 interactors: ABCC1 ITGAV NUF2 SHBG
Entrez ID		6462	563
HPRD ID		01646	01910
Ensembl ID		ENSG00000129214	ENSG00000160862
Uniprot IDs		B0FWH2 B4DYU0 I3L1J1 I3L2X4 P04278	P25311
PDB IDs		1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV 1LHW	1T7V 1T7W 1T7X 1T7Y 1T7Z 1T80 1ZAG 3ES6
Enriched GO Terms of Interacting Partners?		Platelet Activation Extracellular Matrix Disassembly Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Cellular Response To Zinc Ion Endocytosis Vesicle-mediated Transport Response To Wounding Transport Endosomal Transport Cell Activation Response To Zinc Ion Cell Projection Organization Immune System Process MRNA Transcription From RNA Polymerase II Promoter Glucose Metabolic Process MRNA Transcription Neuron Projection Development Movement Of Cell Or Subcellular Component Cellular Response To Cadmium Ion Regulation Of Water Loss Via Skin Formation Of Translation Preinitiation Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cell Morphogenesis Involved In Differentiation Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Receptor-mediated Endocytosis Hexose Metabolic Process Neuron Development Extracellular Matrix Organization Viral Process Cytoplasmic Sequestering Of Protein Regulation Of Defense Response To Virus By Virus Extracellular Structure Organization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Axon Development Antigen Processing And Presentation Of Peptide Antigen Locomotion Negative Regulation Of Growth Monosaccharide Metabolic Process Sperm Entry Negative Regulation Of T Cell Migration Contractile Actin Filament Bundle Assembly Negative Regulation Of Lipoprotein Lipid Oxidation Positive Regulation Of Late Endosome To Lysosome Transport Sorbitol Catabolic Process L-xylitol Metabolic Process L-xylitol Catabolic Process Fructose Biosynthetic Process	Negative Regulation Of Entry Of Bacterium Into Host Cell Entry Of Symbiont Into Host Cell By Promotion Of Host Phagocytosis Primary Spermatocyte Growth Cell Growth Regulation Of Entry Of Bacterium Into Host Cell Negative Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Receptor Biosynthetic Process Apolipoprotein A-I-mediated Signaling Pathway Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Lipoprotein Metabolic Process Positive Regulation Of Osteoblast Proliferation Regulation Of Apoptotic Cell Clearance Regulation Of Lipoprotein Metabolic Process Growth Negative Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Receptor Biosynthetic Process ERK1 And ERK2 Cascade Cobalamin Metabolic Process Negative Regulation Of Lipid Storage Negative Chemotaxis Heterotypic Cell-cell Adhesion Negative Regulation Of Lipid Transport Regulation Of Osteoblast Proliferation Apoptotic Cell Clearance Leukotriene Metabolic Process Endodermal Cell Differentiation Viral Entry Into Host Cell Entry Into Host Cell Substrate Adhesion-dependent Cell Spreading Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Phagocytosis Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Endoderm Formation Regulation Of Lipid Storage
Tagcloud ?		asgr assigned chr distances f1 grin grin1 grin2a grin2b grin2c grin2d grm grm1 grm2 grm3 grm4 grm5 grm6 linkage maps metabotropic mmyhse myhse ppy rr24 shr symbol wtc zi	aggressively aggressiveness analyzing australian biomarkers died dying epidemiological estimate estimates gleason ihc localized minority mrr mrrs muc1 nkx3 nonlethal panel poisson probabilities prostate pten referents retrieved sampling score semiquantitative
Tagcloud (Difference) ?		asgr assigned chr distances f1 grin grin1 grin2a grin2b grin2c grin2d grm grm1 grm2 grm3 grm4 grm5 grm6 linkage maps metabotropic mmyhse myhse ppy rr24 shr symbol wtc zi	aggressively aggressiveness analyzing australian biomarkers died dying epidemiological estimate estimates gleason ihc localized minority mrr mrrs muc1 nkx3 nonlethal panel poisson probabilities prostate pten referents retrieved sampling score semiquantitative
Tagcloud (Intersection) ?