SHBG and FYTTD1

Number of citations of the paper that reports this interaction (PubMedID 15862967)
0

Data Source:
HPRD (two hybrid)

		SHBG	FYTTD1
Description		sex hormone binding globulin	forty-two-three domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytosol Nuclear Speck
	Molecular Function	Steroid Binding Androgen Binding Protein Binding Lipid Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process		MRNA Export From Nucleus MRNA Transport
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Masoprocol Diethylstilbestrol Levonorgestrel Progesterone Spironolactone Toremifene Estrone Tamoxifen Clomifene Dienestrol Hesperetin Zinc Genistein Naringenin Quercetin 4'-Hydroxyflavanone Afimoxifene Estriol Phenolphthalein Norethynodrel Dioxybenzone Zeranol Gestrinone Equol Zinc acetate Zinc chloride Zinc sulfate, unspecified form Estriol tripropionate
Diseases
GWAS		A body shape index ( 34021172) Androgen levels ( 22936694) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Estradiol levels ( 34255042) Glycated hemoglobin levels ( 34059833) Heel bone mineral density ( 30598549) Hormone measurements ( 24049095) Medication use (calcium channel blockers) ( 31015401) Protein quantitative trait loci ( 18464913) Red cell distribution width ( 27863252) Refractive error ( 32231278) Sex hormone levels ( 26014426) Sex hormone-binding globulin levels ( 22675492 22829776) Testosterone levels ( 21998597) Uterine fibroids ( 31649266) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		62 interacting genes: A2M ACP3 ACTA2 ACTB ACTG2 AK2 AKR1B1 AP1B1 AP2A1 APEH APOBEC3C APOD ASB16-AS1 ATP5F1A AZGP1 CD177 CEP192 CLDN4 CLEC4G COL1A2 CTSD DDX3Y DES DSTN EEF1A1 EIF3E EIF3F FLNA FLOT1 FYTTD1 GRB2 HDHD5 HYI JMJD7-PLA2G4B KLK4 MPDU1 MT1F MT1G MT2A MXD4 NOMO1 PACSIN2 PKM PLA2G4A PLP2 PSTPIP1 PSTPIP2 PTGDS RMND5B SEMA3F SLC37A1 SLC37A4 SNAPIN SNRNP70 SORD SPMIP6 SRF SRI TINAGL1 UBE2O UBE3A ZC3H12A	5 interacting genes: ERCC6 EXOSC8 FBXO7 SHBG TSPAN7
Entrez ID		6462	84248
HPRD ID		01646	10909
Ensembl ID		ENSG00000129214	ENSG00000122068
Uniprot IDs		B0FWH2 B0FWH8 I3L145 P04278	Q96QD9
PDB IDs		1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV 1LHW 6PYA 6PYB 6PYF 6ULB
Enriched GO Terms of Interacting Partners?		Extracellular Exosome Protease Binding Cell-cell Junction Fructose Biosynthetic Process Detoxification Of Copper Ion Extracellular Space Glucose 6-phosphate:phosphate Antiporter Activity Cellular Response To Cadmium Ion Lamellipodium Cellular Response To Zinc Ion Cellular Response To Copper Ion Mesenchyme Migration Glucose-6-phosphate Transport Negative Regulation Of Cardiac Muscle Contraction Intracellular Zinc Ion Homeostasis Prostaglandin Metabolic Process Prostanoid Metabolic Process Response To Copper Ion Rough Endoplasmic Reticulum Hexose Metabolic Process Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Striated Muscle Contraction Response To Cadmium Ion Cell-cell Junction Organization Caveola Assembly Carbohydrate Metabolic Process Monosaccharide Metabolic Process Plasma Membrane Raft Assembly Response To Zinc Ion	Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Positive Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Lewy Body Core B-WICH Complex DNA Protection Transcription Elongation By RNA Polymerase I Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Response To Superoxide Response To Oxygen Radical Negative Regulation Of Cell Cycle Phase Transition Androgen Binding Exoribonuclease Complex Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance U4 SnRNA 3'-end Processing Nuclear Polyadenylation-dependent RRNA Catabolic Process Double-strand Break Repair Via Classical Nonhomologous End Joining Single Strand Break Repair Negative Regulation Of Cell Cycle Process Pyrimidine Dimer Repair TRNA Decay RRNA 3'-end Processing Nucleolar Exosome (RNase Complex) Nuclear MRNA Surveillance Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Cell Cycle Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Protein Tyrosine Kinase Activator Activity RRNA Catabolic Process Nuclear Exosome (RNase Complex) Positive Regulation Of Transcription By RNA Polymerase III Exosome (RNase Complex) ATP-dependent DNA Damage Sensor Activity Chromatin-protein Adaptor Activity ATP-dependent Chromatin Remodeler Activity RNA Polymerase Binding Transcription Elongation Factor Complex Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cell Cycle Phase Transition SnRNA 3'-end Processing Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Response To UV-B
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