PLP2 and SLC2A13

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLP2	SLC2A13
Description		proteolipid protein 2	solute carrier family 2 member 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane	Cytoplasm Lysosome Early Endosome Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Apical Plasma Membrane Growth Cone Organelle Membrane Cell Projection Intracellular Membrane-bounded Organelle Cell Body Cell Periphery Astrocyte End-foot
	Molecular Function	Protein Binding Monoatomic Ion Transmembrane Transporter Activity Chemokine Binding	Protease Binding Myo-inositol Transmembrane Transporter Activity Myo-inositol:proton Symporter Activity Protein Binding Transmembrane Transporter Activity ATPase Binding
	Biological Process	Monoatomic Ion Transport Chemotaxis Cytokine-mediated Signaling Pathway Monoatomic Ion Transmembrane Transport	Myo-inositol Transport Transmembrane Transport Transport Across Blood-brain Barrier Positive Regulation Of Amyloid-beta Formation
Pathways			Inositol transporters
Drugs
Diseases
GWAS		Platelet distribution width ( 32888494)	Alzheimer's disease in hypertension ( 31055733) Coronary artery calcification ( 23870195) Crohn's disease ( 28067908) Daytime sleep phenotypes ( 27126917) Disability (impaired activities of daily living) ( 31707593) Inflammatory bowel disease ( 28067908) Insomnia ( 23728906) Parkinson's disease ( 22451204 28011712 32201043) Putamen volume ( 31530798) Sleep quality ( 23728906)
Interacting Genes		79 interacting genes: AQP2 AQP3 AQP6 AQP8 ARFIP2 ARL13B ASGR2 ATP5PF BCAP31 BIK BNIP3 CCR1 CD53 CD79A CERS4 CIAO2A CLDN5 CLN8 CPLX4 CRB3 CREB3L1 CYB561 CYBC1 CYBRD1 DARS2 DLGAP4 DNAJC1 EBP ELOVL5 ELP1 EVI2A FAM209A FAM210B FATE1 FCER1G FKBP7 FNDC9 GPR151 GPX8 HSBP1L1 HSD17B11 HSD17B13 KASH5 LHFPL1 LHFPL5 LMNA LRRC4C MGST3 MUC1 NDRG4 PACC1 PDZK1IP1 PIGP PSCA PTGES PVR REEP4 RETREG3 RNF5 SAR1A SCN3B SGPL1 SHBG SLC10A6 SLC14A2 SLC18A1 SLC2A13 SLC35H1 SPG21 SPN THAP4 TM4SF19 TMEM14B TMEM31 TMEM51 TMEM79 TMPRSS2 TMX2 VKORC1	4 interacting genes: CYP4F2 FXYD6-FXYD2 PLP2 RIC8A
Entrez ID		5355	114134
HPRD ID		02121	15363
Ensembl ID		ENSG00000102007	ENSG00000151229
Uniprot IDs		Q04941	Q96QE2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding Water Channel Activity Water Transport Renal Water Transport One-carbon Compound Transport Urea Transmembrane Transport Urea Transport Fluid Transport PH-gated Chloride Channel Activity Mitochondrial Membrane Channel Activity Apical Plasma Membrane Ascorbate Homeostasis Steroid Dehydrogenase Activity Organic Hydroxy Compound Transport Endoplasmic Reticulum-autophagosome Adaptor Activity Transmembrane Monodehydroascorbate Reductase Activity Glutathione Peroxidase Activity Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Transmembrane Transport Urea Transmembrane Transporter Activity Identical Protein Binding Glycerol Transmembrane Transport Plasma Membrane Substrate Localization To Autophagosome Ammonium Channel Activity Polyol Transmembrane Transport	Alpha-tocopherol Omega-hydroxylase Activity Negative Regulation Of Icosanoid Secretion Leukotriene B4 Catabolic Process 20-hydroxy-leukotriene B4 Omega Oxidase Activity Alkane 1-monooxygenase Activity 20-aldehyde-leukotriene B4 20-monooxygenase Activity Leukotriene B4 Metabolic Process Arachidonate Omega-hydroxylase Activity Coagulation Blood Coagulation Hemostasis Leukotriene-B4 20-monooxygenase Activity Pressure Natriuresis Cell-cell Adhesion Involved In Gastrulation Positive Regulation Of Potassium Ion Export Across Plasma Membrane Activation Of Blood Coagulation Via Clotting Cascade Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phospholipid Scrambling Calcium Activated Phosphatidylcholine Scrambling Phosphatidylserine Exposure On Blood Platelet Phylloquinone Catabolic Process Long-chain Fatty Acid Omega-hydroxylase Activity Vitamin K Catabolic Process Vitamin E Metabolic Process Menaquinone Metabolic Process Fatty Acid Omega-oxidation Menaquinone Catabolic Process Negative Regulation Of Cell Volume Chemokine Binding Long-chain Fatty Acid Catabolic Process Negative Regulation Of Fatty Acid Transport Arachidonate Epoxygenase Activity Regulation Of Body Fluid Levels Omega-hydroxylase P450 Pathway Voltage-gated Chloride Channel Activity Bleb Assembly Calcium-activated Cation Channel Activity Voltage-gated Monoatomic Ion Channel Activity Monoatomic Ion Transmembrane Transporter Activity Epoxygenase P450 Pathway Vitamin K Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Cell Migration Involved In Gastrulation Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Phagocytosis, Engulfment Intracellularly Calcium-gated Chloride Channel Activity Positive Regulation Of Icosanoid Secretion Ketone Catabolic Process Renal Water Homeostasis Phospholipid Scramblase Activity
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