ATP6V1E1 and MESDC2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ATP6V1E1	MESDC2
Gene Name		ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1	mesoderm development candidate 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Lysosomal Membrane Endosome Cytosol Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting Two-sector ATPase Complex, Catalytic Domain Extracellular Vesicular Exosome	Cellular_component Endoplasmic Reticulum Plasma Membrane
	Molecular Function	Protein Binding Hydrogen-exporting ATPase Activity, Phosphorylative Mechanism Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding	Molecular_function Low-density Lipoprotein Particle Receptor Binding
	Biological Process	Cellular Iron Ion Homeostasis Metabolic Process Insulin Receptor Signaling Pathway ATP Hydrolysis Coupled Proton Transport Proton Transport Transferrin Transport Interaction With Host Transmembrane Transport Phagosome Maturation	Protein Folding Mesoderm Development Wnt Signaling Pathway Protein Localization To Cell Surface
Pathways		Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ALDOA ALDOB ALDOC APP ATP6V0E1 ATP6V1G1 ATP6V1G2 ATP6V1H MESDC2 SLC9A3R1 SOS1 TRAF6 XRCC6	9 interactors: APP ATP6V1E1 BRD4 KPNB1 LRP5 PSMA5 RFC3 SNX5 SNX7
Entrez ID		529	23184
HPRD ID		00163	12129
Ensembl ID		ENSG00000131100	ENSG00000117899
Uniprot IDs		P36543 Q53Y06	Q14696
PDB IDs
Enriched GO Terms of Interacting Partners?		Fructose 1,6-bisphosphate Metabolic Process Transferrin Transport Homeostatic Process Phagosome Maturation Transition Metal Ion Homeostasis Insulin Receptor Signaling Pathway Cellular Homeostasis Cellular Response To Insulin Stimulus Cellular Ion Homeostasis Iron Ion Transport Cellular Iron Ion Homeostasis Fructose Metabolic Process Cellular Chemical Homeostasis Interaction With Host Ion Homeostasis Response To Insulin Iron Ion Homeostasis Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Metal Ion Homeostasis Hydrogen Ion Transmembrane Transport Response To Organonitrogen Compound Cellular Cation Homeostasis Response To Peptide Hormone Chemical Homeostasis Metal Ion Homeostasis Cellular Response To Organonitrogen Compound Gluconeogenesis Enzyme Linked Receptor Protein Signaling Pathway Response To Peptide Proton Transport Cell Surface Receptor Signaling Pathway Hexose Biosynthetic Process Cellular Response To Hormone Stimulus Glycolytic Process Monovalent Inorganic Cation Transport Vacuolar Acidification Response To Stimulus Pyruvate Metabolic Process Intracellular PH Reduction Metal Ion Transport Carbohydrate Catabolic Process Glucose Metabolic Process PH Reduction Carbohydrate Biosynthetic Process Response To Hormone Protein Complex Assembly Response To Organic Substance Platelet Activation	Positive Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Positive Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Endocytosis Regulation Of Cell Cycle Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Synaptic Growth At Neuromuscular Junction Cell-cell Signaling Involved In Mammary Gland Development Cholesterol Metabolic Process Viral Process Positive Regulation Of Canonical Wnt Signaling Pathway Sterol Metabolic Process Homeostatic Process Collateral Sprouting In Absence Of Injury Protein Transport Vesicle-mediated Transport Transition Metal Ion Homeostasis Establishment Of Protein Localization Negative Regulation Of DNA Damage Checkpoint Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Histone H3-K14 Acetylation Positive Regulation Of Wnt Signaling Pathway G1/S Transition Of Mitotic Cell Cycle Retinal Blood Vessel Morphogenesis Collateral Sprouting Axon Midline Choice Point Recognition Cellular Homeostasis Extracellular Matrix-cell Signaling Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Glucose Catabolic Process Mitotic Cell Cycle Axon Choice Point Recognition Bone Marrow Development Negative Regulation Of Catalytic Activity Cellular Response To Stimulus Vesicle Organization Negative Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		ae2 apical aqp9 aquaporin bapta bdkrb1 bdkrb2 caput cauda ciliated colocalize corpus ducts efferent epididymal epididymidis epididymis exchanger glycerol kks lcm microdissection nonciliated official pole solute stereocilia symbol uniform
Tagcloud (Difference) ?		ae2 apical aqp9 aquaporin bapta bdkrb1 bdkrb2 caput cauda ciliated colocalize corpus ducts efferent epididymal epididymidis epididymis exchanger glycerol kks lcm microdissection nonciliated official pole solute stereocilia symbol uniform
Tagcloud (Intersection) ?