MESD and CNOT9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MESD	CNOT9
Description		mesoderm development LRP chaperone	CCR4-NOT transcription complex subunit 9
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane	P-body Nucleus Cytoplasm Cytosol Membrane CCR4-NOT Complex CCR4-NOT Core Complex Protein-containing Complex
	Molecular Function	Protein Binding Identical Protein Binding Protein Folding Chaperone Low-density Lipoprotein Particle Receptor Binding	Transcription Coactivator Activity Epidermal Growth Factor Receptor Binding Protein Binding Kinase Binding Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Protein Localization To Cell Surface Protein Localization To Plasma Membrane Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering	Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Catabolic Process Regulation Of Translation Sex Differentiation Negative Regulation Of Translation Cytokine-mediated Signaling Pathway Regulatory NcRNA-mediated Gene Silencing Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of DNA-templated Transcription
Pathways			Deadenylation of mRNA Activation of anterior HOX genes in hindbrain development during early embryogenesis TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain M-decay: degradation of maternal mRNAs by maternally stored factors
Drugs
Diseases
GWAS
Interacting Genes		78 interacting genes: - ABCG8 ABITRAM ACBD7 AKIRIN2 AKNAD1 AKT1 APP ARB2A ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KLHL20 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MAPDA MCM9 MELTF MKNK2 MRM1 MTNR1A NAA35 NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SLC6A20 SMARCB1 SNX5 SNX7 TEKTL1 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844	11 interacting genes: AKT1 EGFR GADD45A GADD45B GADD45G GIGYF1 GIGYF2 GRB10 MESD MYB OBI1
Entrez ID		23184	9125
HPRD ID		12129	08828
Ensembl ID		ENSG00000117899	ENSG00000144580
Uniprot IDs		Q14696	D5MQE1 Q92600
PDB IDs			2FV2 4CRU 4CRV 4CT6 4CT7 5LSW 5ONA 5ONB 6HOM 6HON 9FL8
Enriched GO Terms of Interacting Partners?		Protein Binding Proton-transporting Two-sector ATPase Complex, Catalytic Domain	Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of P38MAPK Cascade Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of P38MAPK Cascade Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Protein Localization To Membrane Positive Regulation Of Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Regulation Of Cell Cycle Enzyme-linked Receptor Protein Signaling Pathway Response To UV-A Kinase Binding Positive Regulation Of JNK Cascade Protein-containing Complex Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Signal Transduction Regulation Of Phosphorylation Regulation Of Apoptotic Process Regulation Of JNK Cascade Regulation Of G1/S Transition Of Mitotic Cell Cycle Embryonic Organ Development Regulation Of Programmed Cell Death Regulation Of Glycogen Biosynthetic Process Regulation Of Protein Localization To Membrane Positive Regulation Of MAPK Cascade Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Apoptotic Process Regulation Of Glycogen Metabolic Process Positive Regulation Of Programmed Cell Death Regulation Of Phosphorus Metabolic Process Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Epidermal Growth Factor Stimulus Negative Regulation Of Translational Initiation Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Metabolic Process Positive Regulation Of Phosphorylation Response To Epidermal Growth Factor Regulation Of MAPK Cascade Positive Regulation Of Fibroblast Proliferation Positive Regulation Of MiRNA Transcription Regulation Of TRNA Methylation Regulation Of D-glucose Import Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Multivesicular Body, Internal Vesicle Lumen Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Cycle G1/S Phase Transition Epidermal Growth Factor Receptor Signaling Pathway
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