MESD and AKNAD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MESD	AKNAD1
Description		mesoderm development LRP chaperone	AKNA domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Folding Chaperone Low-density Lipoprotein Particle Receptor Binding	Protein Binding
	Biological Process	Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Protein Localization To Cell Surface Protein Localization To Plasma Membrane Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways
Drugs
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065) Fat distribution (HIV) ( 21897333) LDL cholesterol levels ( 32203549)
Interacting Genes		78 interacting genes: - ABCG8 ABITRAM ACBD7 AKIRIN2 AKNAD1 AKT1 APP ARB2A ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KLHL20 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MAPDA MCM9 MELTF MKNK2 MRM1 MTNR1A NAA35 NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SLC6A20 SMARCB1 SNX5 SNX7 TEKTL1 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844	3 interacting genes: APP MESD NOS1AP
Entrez ID		23184	254268
HPRD ID		12129	11325
Ensembl ID		ENSG00000117899	ENSG00000162641
Uniprot IDs		Q14696	Q5T1N1
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Proton-transporting Two-sector ATPase Complex, Catalytic Domain	Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Low-density Lipoprotein Particle Receptor Binding Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Acetylcholine Receptor Activator Activity PTB Domain Binding Regulation Of Calcium Ion Transmembrane Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Calcium Ion Transport Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Positive Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Blood Circulation Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Regulation Of Monoatomic Ion Transmembrane Transport Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Heart Rate By Chemical Signal Regulation Of Wnt Signaling Pathway Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Axon Choice Point Recognition Regulation Of Metal Ion Transport Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Heparan Sulfate Binding Signaling Receptor Activator Activity
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