MESD and BORCS8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MESD	BORCS8
Description		mesoderm development LRP chaperone	BLOC-1 related complex subunit 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane	Lysosome Lysosomal Membrane Membrane Cytoplasmic Side Of Lysosomal Membrane BORC Complex
	Molecular Function	Protein Binding Identical Protein Binding Protein Folding Chaperone Low-density Lipoprotein Particle Receptor Binding	Protein Binding
	Biological Process	Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Protein Localization To Cell Surface Protein Localization To Plasma Membrane Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering	Heart Development Lysosome Localization Regulation Of Endosome Size Regulation Of Lysosome Size Organelle Transport Along Microtubule
Pathways
Drugs
Diseases
GWAS			Height ( 28552196)
Interacting Genes		78 interacting genes: - ABCG8 ABITRAM ACBD7 AKIRIN2 AKNAD1 AKT1 APP ARB2A ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KLHL20 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MAPDA MCM9 MELTF MKNK2 MRM1 MTNR1A NAA35 NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SLC6A20 SMARCB1 SNX5 SNX7 TEKTL1 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844	6 interacting genes: AGR2 CTAG1A CTAG1B MESD P2RX5 TEX11
Entrez ID		23184	729991
HPRD ID		12129	19682
Ensembl ID		ENSG00000117899	ENSG00000254901
Uniprot IDs		Q14696	Q96FH0
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Proton-transporting Two-sector ATPase Complex, Catalytic Domain	TRNA Threonylcarbamoyladenosine Metabolic Process Identical Protein Binding ATP-gated Ion Channel Activity Positive Regulation Of Protein Localization To Membrane Meiotic Gene Conversion Regulation Of Cellular Localization Osteoclast Maturation Gene Conversion Ligand-gated Monoatomic Anion Channel Activity Lung Goblet Cell Differentiation Male Meiosis Chromosome Segregation Regulation Of Protein Localization To Membrane Positive Regulation Of PERK-mediated Unfolded Protein Response TRNA Metabolic Process Regulation Of Skeletal Muscle Tissue Regeneration Purinergic Nucleotide Receptor Activity Extracellularly ATP-gated Monoatomic Cation Channel Activity Positive Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Central Element Chiasma Assembly Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Calcium Ion Import Across Plasma Membrane Dystroglycan Binding Voltage-gated Monoatomic Ion Channel Activity Positive Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Developmental Growth Regulation Of Calcium Ion Import Across Plasma Membrane Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Receptor Clustering Meiotic Chromosome Segregation Mucus Secretion Regulation Of IRE1-mediated Unfolded Protein Response Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Receptor Clustering Resolution Of Meiotic Recombination Intermediates Ectopic Germ Cell Programmed Cell Death Purinergic Nucleotide Receptor Signaling Pathway Regulation Of Calcium Ion Transport Into Cytosol Digestive Tract Morphogenesis Programmed Cell Death Involved In Cell Development Synaptonemal Complex Assembly
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