MESD and CYP4F11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MESD	CYP4F11
Description		mesoderm development LRP chaperone	cytochrome P450 family 4 subfamily F member 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Folding Chaperone Low-density Lipoprotein Particle Receptor Binding	Monooxygenase Activity Fatty Acid Binding Iron Ion Binding Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Heme Binding Metal Ion Binding Arachidonate Omega-hydroxylase Activity Long-chain Fatty Acid Omega-hydroxylase Activity
	Biological Process	Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Protein Localization To Cell Surface Protein Localization To Plasma Membrane Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering	Lipid Metabolic Process Fatty Acid Metabolic Process Blood Coagulation Arachidonate Metabolic Process Oxylipin Biosynthetic Process Menaquinone Catabolic Process Phylloquinone Catabolic Process Vitamin K Catabolic Process Omega-hydroxylase P450 Pathway Cytochrome Metabolic Process
Pathways			Fatty acids Miscellaneous substrates Eicosanoids Synthesis of Leukotrienes (LT) and Eoxins (EX)
Drugs
Diseases
GWAS
Interacting Genes		78 interacting genes: - ABCG8 ABITRAM ACBD7 AKIRIN2 AKNAD1 AKT1 APP ARB2A ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KLHL20 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MAPDA MCM9 MELTF MKNK2 MRM1 MTNR1A NAA35 NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SLC6A20 SMARCB1 SNX5 SNX7 TEKTL1 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844	2 interacting genes: MESD POT1
Entrez ID		23184	57834
HPRD ID		12129	07101
Ensembl ID		ENSG00000117899	ENSG00000171903
Uniprot IDs		Q14696	Q9HBI6
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Proton-transporting Two-sector ATPase Complex, Catalytic Domain	Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Positive Regulation Of DNA Strand Elongation Telomeric D-loop Binding Telomere Assembly Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Ethanolamine Transport Ethanolamine Transmembrane Transporter Activity Single-stranded Telomeric DNA Binding Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Telomerase Inhibitor Activity Nuclear Telomere Cap Complex Shelterin Complex Telomeric D-loop Disassembly DEAD/H-box RNA Helicase Binding Establishment Of Protein Localization To Telomere Choline Transmembrane Transporter Activity Choline Transport G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Amine Transport Positive Regulation Of Receptor Clustering Telomere Capping Regulation Of DNA Strand Elongation Regulation Of Receptor Clustering Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Phosphatidylcholine Biosynthetic Process Positive Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Cell Surface Low-density Lipoprotein Particle Receptor Binding Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding RNA-templated DNA Biosynthetic Process Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Biosynthetic Process Regulation Of Telomere Maintenance Via Telomere Lengthening Mesoderm Development Protein Folding Chaperone Phosphatidylcholine Metabolic Process Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization
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