ATP6V1E1 and ALDOC

Number of citations of the paper that reports this interaction (PubMedID 11399750)
0

Data Source:
BioGRID (two hybrid)

		ATP6V1E1	ALDOC
Description		ATPase H+ transporting V1 subunit E1	aldolase, fructose-bisphosphate C
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GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V1 Domain Cytoplasm Lysosomal Membrane Endosome Cytosol Plasma Membrane Microvillus Membrane Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Clathrin-coated Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Proton-transporting Two-sector ATPase Complex, Catalytic Domain Synapse Extracellular Exosome	Extracellular Region Cytosol Cytoskeleton Secretory Granule Lumen Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Lyase Activity
	Biological Process	Monoatomic Ion Transport Regulation Of Macroautophagy Synaptic Vesicle Lumen Acidification Proton Transmembrane Transport	Fructose Metabolic Process Gluconeogenesis Glycolytic Process Fructose 1,6-bisphosphate Metabolic Process Epithelial Cell Differentiation
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy	Neutrophil degranulation Glycolysis Gluconeogenesis
Drugs		Tiludronic acid
Diseases
GWAS
Interacting Genes		14 interacting genes: ALDOA ALDOB ALDOC APP ATP6V0E1 ATP6V1G1 ATP6V1G2 ATP6V1H HSPB2 MESD NHERF1 SOS1 TRAF6 XRCC6	9 interacting genes: ANKS1A ATP6V1E1 CFTR ERBB2 FMR1 LNX1 MAP2K3 PLD2 SQLE
Entrez ID		529	230
HPRD ID		00163	02386
Ensembl ID		ENSG00000131100	ENSG00000109107
Uniprot IDs		P36543 Q53Y06	A0A024QZ64 P09972
PDB IDs		6WLZ 6WM2 6WM3 6WM4 7U4T 7UNF	1XFB
Enriched GO Terms of Interacting Partners?		Fructose-bisphosphate Aldolase Activity Proton-transporting ATPase Activity, Rotational Mechanism Fructose 1,6-bisphosphate Metabolic Process Homeostatic Process Vacuolar Proton-transporting V-type ATPase, V1 Domain Fructose Metabolic Process Extrinsic Component Of Synaptic Vesicle Membrane Cellular Homeostasis Proton-transporting V-type ATPase Complex ADP Catabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Lyase Activity Glycolytic Process Growth Factor Receptor Binding Proton Transmembrane Transport ADP Metabolic Process Nucleoside Diphosphate Catabolic Process Fructose Binding Ribonucleoside Diphosphate Catabolic Process Regulation Of Macroautophagy Pyruvate Metabolic Process Cytoskeletal Protein Binding Ribonucleoside Diphosphate Metabolic Process Purine Ribonucleotide Catabolic Process Nucleoside Diphosphate Metabolic Process Purine Nucleotide Catabolic Process Intracellular Chemical Homeostasis Vacuolar Proton-transporting V-type ATPase Complex Regulation Of Phosphorus Metabolic Process Nucleotide Catabolic Process Synaptic Vesicle Lumen Acidification Nicotinamide Nucleotide Metabolic Process Carbohydrate Catabolic Process Secretory Granule Lumen Ficolin-1-rich Granule Lumen Nucleoside Phosphate Catabolic Process Fc-epsilon Receptor Signaling Pathway ATP Hydrolysis Activity Regulation Of Autophagy Low-density Lipoprotein Particle Receptor Binding Monoatomic Cation Transport Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis ATP Metabolic Process Hexose Metabolic Process Organophosphate Catabolic Process Clathrin-coated Vesicle Membrane Cytosol Monosaccharide Metabolic Process Vacuolar Acidification	Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex, Catalytic Domain Cholesterol Biosynthetic Process Regulation Of Transmembrane Transporter Activity Developmental Maturation Positive Regulation Of Anion Channel Activity Steroid Biosynthetic Process Sterol Biosynthetic Process Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding PDZ Domain Binding Regulation Of Monoatomic Ion Transmembrane Transporter Activity ERBB3:ERBB2 Complex Dendritic Filopodium Histone H3 Reader Activity Positive Regulation Of Intracellular Transport Of Viral Material Cellular Response To Sorbitol Squalene Monooxygenase Activity Mesonephric Duct Formation Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Mesonephric Nephron Morphogenesis Ureteric Bud Elongation Pronephric Nephron Tubule Development Hepatoblast Differentiation Regulation Of Pronephros Size Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Positive Regulation Of Monoatomic Anion Transport RNA Polymerase I Core Binding Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Negative Regulation Of Long-term Synaptic Depression Growth Cone Filopodium Response To Biphenyl Regulation Of Branch Elongation Involved In Ureteric Bud Branching Mesonephric Duct Morphogenesis Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Proton-transporting Two-sector ATPase Complex Sterol Metabolic Process Cholesterol Metabolic Process Positive Regulation Of Tooth Mineralization Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Lipid Biosynthetic Process Cell Maturation Regulation Of Vesicle-mediated Transport Negative Regulation Of Immature T Cell Proliferation In Thymus Positive Regulation Of Kinase Activity Positive Regulation Of Protein Kinase Activity Negative Regulation Of Immature T Cell Proliferation ErbB-3 Class Receptor Binding Presynaptic Membrane
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