MESD and COX14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MESD	COX14
Description		mesoderm development LRP chaperone	cytochrome c oxidase assembly factor COX14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Folding Chaperone Low-density Lipoprotein Particle Receptor Binding	Protein Binding
	Biological Process	Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Protein Localization To Cell Surface Protein Localization To Plasma Membrane Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering	Mitochondrial Cytochrome C Oxidase Assembly
Pathways			Complex IV assembly
Drugs
Diseases
GWAS			Diastolic blood pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		78 interacting genes: - ABCG8 ABITRAM ACBD7 AKIRIN2 AKNAD1 AKT1 APP ARB2A ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KLHL20 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MAPDA MCM9 MELTF MKNK2 MRM1 MTNR1A NAA35 NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SLC6A20 SMARCB1 SNX5 SNX7 TEKTL1 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844	3 interacting genes: LMNA MESD TMEM31
Entrez ID		23184	84987
HPRD ID		12129	17495
Ensembl ID		ENSG00000117899	ENSG00000178449
Uniprot IDs		Q14696	Q96I36
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Proton-transporting Two-sector ATPase Complex, Catalytic Domain	Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Lamin Filament DNA Double-strand Break Attachment To Nuclear Envelope Ventricular Cardiac Muscle Cell Development Nuclear Pore Localization Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Mesenchymal Cell Proliferation Structural Constituent Of Nuclear Lamina Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Receptor Clustering Nuclear Lamina Protein Localization To Nuclear Envelope Localization Within Membrane Regulation Of Receptor Clustering Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Nuclear Envelope Organization Nuclear Migration Low-density Lipoprotein Particle Receptor Binding Nucleus Localization Protein Localization To Cell Surface Nuclear Lumen Negative Regulation Of Muscle Hypertrophy Cardiac Muscle Cell Development Regulation Of Mesenchymal Cell Proliferation Negative Regulation Of Cardiac Muscle Hypertrophy Regulation Of Release Of Cytochrome C From Mitochondria Cardiac Cell Development Regulation Of Protein Localization
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