ATP6V1E1 and ALDOB

Number of citations of the paper that reports this interaction (PMID 11399750)
37

Data Source:
BioGRID (two hybrid)
HPRD (in vitro)

		ATP6V1E1	ALDOB
Gene Name		ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1	aldolase B, fructose-bisphosphate
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Lysosomal Membrane Endosome Cytosol Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting Two-sector ATPase Complex, Catalytic Domain Extracellular Vesicular Exosome	Microtubule Organizing Center Cytosol Centriolar Satellite Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Hydrogen-exporting ATPase Activity, Phosphorylative Mechanism Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Identical Protein Binding ATPase Binding Fructose-1-phosphate Aldolase Activity Fructose Binding
	Biological Process	Cellular Iron Ion Homeostasis Metabolic Process Insulin Receptor Signaling Pathway ATP Hydrolysis Coupled Proton Transport Proton Transport Transferrin Transport Interaction With Host Transmembrane Transport Phagosome Maturation	Carbohydrate Metabolic Process Fructose Metabolic Process Fructose Catabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process NADH Oxidation Pathogenesis Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of ATPase Activity Small Molecule Metabolic Process Vacuolar Proton-transporting V-type ATPase Complex Assembly
Pathways		Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor	Fructose catabolism Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs
Diseases
GWAS			Liver enzyme levels (alkaline phosphatase) ( 22001757)
Protein-Protein Interactions		13 interactors: ALDOA ALDOB ALDOC APP ATP6V0E1 ATP6V1G1 ATP6V1G2 ATP6V1H MESDC2 SLC9A3R1 SOS1 TRAF6 XRCC6	8 interactors: AGXT2 ALDOA APP ATP6V1E1 HIVEP1 HSPA8 MUC20 TXN2
Entrez ID		529	229
HPRD ID		00163	01972
Ensembl ID		ENSG00000131100	ENSG00000136872
Uniprot IDs		P36543 Q53Y06	P05062
PDB IDs			1QO5 1XDL 1XDM
Enriched GO Terms of Interacting Partners?		Fructose 1,6-bisphosphate Metabolic Process Transferrin Transport Homeostatic Process Phagosome Maturation Transition Metal Ion Homeostasis Insulin Receptor Signaling Pathway Cellular Homeostasis Cellular Response To Insulin Stimulus Cellular Ion Homeostasis Iron Ion Transport Cellular Iron Ion Homeostasis Fructose Metabolic Process Cellular Chemical Homeostasis Interaction With Host Ion Homeostasis Response To Insulin Iron Ion Homeostasis Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Metal Ion Homeostasis Hydrogen Ion Transmembrane Transport Response To Organonitrogen Compound Cellular Cation Homeostasis Response To Peptide Hormone Chemical Homeostasis Metal Ion Homeostasis Cellular Response To Organonitrogen Compound Gluconeogenesis Enzyme Linked Receptor Protein Signaling Pathway Response To Peptide Proton Transport Cell Surface Receptor Signaling Pathway Hexose Biosynthetic Process Cellular Response To Hormone Stimulus Glycolytic Process Monovalent Inorganic Cation Transport Vacuolar Acidification Response To Stimulus Pyruvate Metabolic Process Intracellular PH Reduction Metal Ion Transport Carbohydrate Catabolic Process Glucose Metabolic Process PH Reduction Carbohydrate Biosynthetic Process Response To Hormone Protein Complex Assembly Response To Organic Substance Platelet Activation	Cellular Homeostasis Platelet Degranulation L-alanine Catabolic Process, By Transamination Negative Regulation Of Fibril Organization Secretion By Cell Homeostatic Process Synaptic Growth At Neuromuscular Junction Glycine Biosynthetic Process, By Transamination Of Glyoxylate Secretion Collateral Sprouting In Absence Of Injury Regulation Of Fibril Organization Glyoxylate Catabolic Process Transition Metal Ion Homeostasis Response To Wounding L-alanine Metabolic Process L-alanine Catabolic Process Fructose 1,6-bisphosphate Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Clathrin Coat Disassembly Platelet Activation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Hepatocyte Growth Factor Receptor Signaling Pathway Glyoxylate Metabolic Process Neuron Remodeling Protein Homooligomerization
Tagcloud ?		ae2 apical aqp9 aquaporin bapta bdkrb1 bdkrb2 caput cauda ciliated colocalize corpus ducts efferent epididymal epididymidis epididymis exchanger glycerol kks lcm microdissection nonciliated official pole solute stereocilia symbol uniform	aldolase ambp anchor anonymous backcross bikunin d4h9s3e d4nds4 d9s3 dehydratase galt hexabrachion homologues hsa9 hsa9q hxb ifa interspecific levulinate localizations mmu4 orm orosomucoid pax pax5 synteny typed tyrp
Tagcloud (Difference) ?		ae2 apical aqp9 aquaporin bapta bdkrb1 bdkrb2 caput cauda ciliated colocalize corpus ducts efferent epididymal epididymidis epididymis exchanger glycerol kks lcm microdissection nonciliated official pole solute stereocilia symbol uniform	aldolase ambp anchor anonymous backcross bikunin d4h9s3e d4nds4 d9s3 dehydratase galt hexabrachion homologues hsa9 hsa9q hxb ifa interspecific levulinate localizations mmu4 orm orosomucoid pax pax5 synteny typed tyrp
Tagcloud (Intersection) ?