MESDC2 and SNX7

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MESDC2	SNX7
Gene Name		mesoderm development candidate 2	sorting nexin 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Endoplasmic Reticulum Plasma Membrane	Endosome Extrinsic Component Of Membrane Cytoplasmic Vesicle Membrane
	Molecular Function	Molecular_function Low-density Lipoprotein Particle Receptor Binding	Protein Binding Phosphatidylinositol Binding
	Biological Process	Protein Folding Mesoderm Development Wnt Signaling Pathway Protein Localization To Cell Surface	Endocytosis Protein Transport Vesicle Organization
Pathways
Drugs
Diseases
GWAS			Dental caries ( 23259602) Proinsulin levels ( 21873549)
Protein-Protein Interactions		9 interactors: APP ATP6V1E1 BRD4 KPNB1 LRP5 PSMA5 RFC3 SNX5 SNX7	7 interactors: BIRC3 HGS HMOX2 MAGEA11 MESDC2 POLR2L TEX11
Entrez ID		23184	51375
HPRD ID		12129	15416
Ensembl ID		ENSG00000117899	ENSG00000162627
Uniprot IDs		Q14696	B4DP69 E9PNL2 Q9UNH6
PDB IDs			3IQ2
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Positive Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Endocytosis Regulation Of Cell Cycle Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Synaptic Growth At Neuromuscular Junction Cell-cell Signaling Involved In Mammary Gland Development Cholesterol Metabolic Process Viral Process Positive Regulation Of Canonical Wnt Signaling Pathway Sterol Metabolic Process Homeostatic Process Collateral Sprouting In Absence Of Injury Protein Transport Vesicle-mediated Transport Transition Metal Ion Homeostasis Establishment Of Protein Localization Negative Regulation Of DNA Damage Checkpoint Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Histone H3-K14 Acetylation Positive Regulation Of Wnt Signaling Pathway G1/S Transition Of Mitotic Cell Cycle Retinal Blood Vessel Morphogenesis Collateral Sprouting Axon Midline Choice Point Recognition Cellular Homeostasis Extracellular Matrix-cell Signaling Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Glucose Catabolic Process Mitotic Cell Cycle Axon Choice Point Recognition Bone Marrow Development Negative Regulation Of Catalytic Activity Cellular Response To Stimulus Vesicle Organization Negative Regulation Of Cellular Protein Metabolic Process
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