MESD and MELTF

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MESD	MELTF
Description		mesoderm development LRP chaperone	melanotransferrin
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane	Extracellular Region Extracellular Space Early Endosome Endoplasmic Reticulum Lumen Plasma Membrane Cell Surface Membrane Recycling Endosome Extracellular Exosome Side Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Folding Chaperone Low-density Lipoprotein Particle Receptor Binding	Iron Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Protein Localization To Cell Surface Protein Localization To Plasma Membrane Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering	Regulation Of Cell Growth Monoatomic Ion Transport Iron Ion Transport Positive Regulation Of Plasminogen Activation Regulation Of Cell Population Proliferation Positive Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways			Post-translational modification: synthesis of GPI-anchored proteins Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS			Malaria ( 31844061)
Interacting Genes		78 interacting genes: - ABCG8 ABITRAM ACBD7 AKIRIN2 AKNAD1 AKT1 APP ARB2A ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KLHL20 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MAPDA MCM9 MELTF MKNK2 MRM1 MTNR1A NAA35 NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SLC6A20 SMARCB1 SNX5 SNX7 TEKTL1 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844	11 interacting genes: CFTR CYSRT1 DERL1 DERL2 DERL3 HPGDS KRTAP1-1 KRTAP10-8 MESD NBPF19 NOTCH2NLA
Entrez ID		23184	4241
HPRD ID		12129	01122
Ensembl ID		ENSG00000117899	ENSG00000163975
Uniprot IDs		Q14696	P08582 Q53XS6
PDB IDs			6XR0
Enriched GO Terms of Interacting Partners?		Protein Binding Proton-transporting Two-sector ATPase Complex, Catalytic Domain	Signal Recognition Particle Binding Response To Endoplasmic Reticulum Stress Regulation Of Cellular Localization Negative Regulation Of Protein Exit From Endoplasmic Reticulum Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Retrograde Protein Transport, ER To Cytosol ERAD Pathway Regulation Of Retrograde Protein Transport, ER To Cytosol Retrograde Protein Transport, ER To Cytosol Regulation Of Protein Exit From Endoplasmic Reticulum Regulation Of Intracellular Protein Transport Regulation Of Protein Transport Protein Exit From Endoplasmic Reticulum Regulation Of Protein Localization Negative Regulation Of Intracellular Protein Transport Regulation Of Establishment Of Protein Localization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Protein Destabilization Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Regulation Of Intracellular Transport Negative Regulation Of Intracellular Transport Early Endosome Positive Regulation Of Anion Channel Activity Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Histone H3K27 Acetyltransferase Activity Peptide Crotonyltransferase Activity Derlin-1-VIMP Complex Response To Unfolded Protein Positive Regulation Of Monoatomic Anion Transport N-terminal Peptidyl-lysine Acetylation Histone H3K18 Acetyltransferase Activity Thigmotaxis Peptide Lactyltransferase (CoA-dependent) Activity Prostaglandin-D Synthase Activity Negative Regulation Of Male Germ Cell Proliferation Protein-containing Complex Binding Keratin Filament
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