PGK1 and GAPDH

Number of citations of the paper that reports this interaction (PMID 8075252)
0

Data Source:
HPRD (in vitro, in vivo)

		PGK1	GAPDH
Gene Name		phosphoglycerate kinase 1	glyceraldehyde-3-phosphate dehydrogenase
Image
Gene Ontology Annotations	Cellular Component	Cytosol Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm Lipid Particle Cytosol Plasma Membrane Microtubule Cytoskeleton Membrane Ribonucleoprotein Complex Nuclear Membrane Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome GAIT Complex
	Molecular Function	Phosphoglycerate Kinase Activity Protein Binding ATP Binding	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding Microtubule Binding Peptidyl-cysteine S-nitrosylase Activity Identical Protein Binding NADP Binding NAD Binding
	Biological Process	Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Pathogenesis Phosphorylation Epithelial Cell Differentiation Small Molecule Metabolic Process	Microtubule Cytoskeleton Organization Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Pathogenesis Negative Regulation Of Translation Peptidyl-cysteine S-trans-nitrosylation Small Molecule Metabolic Process Protein Stabilization Neuron Apoptotic Process Oxidation-reduction Process Cellular Response To Interferon-gamma
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates	Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs			NADH Nicotinamide-Adenine-Dinucleotide Adenosine-5-Diphosphoribose Thionicotinamide-Adenine-Dinucleotide 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE
Diseases
GWAS
Protein-Protein Interactions		7 interactors: DISC1 GAPDH HIF1A HSPH1 PCNA SUMO4 YWHAQ	75 interactors: ACD ACTB ACTC1 ANXA1 ANXA7 APP AR ARL15 ATN1 ATXN1 BID BPGM BTBD2 CAMK1 CAMK2B CAMK4 CDKN1A CDKN2A CHP1 DYNLL1 EGFR FKBP6 GADD45A GAS7 GOT2 GRM1 GSK3B HES1 HNF4G HTT KARS KAT5 KCNE3 LAMA4 LAMTOR5 LIG4 MAPK1 MYOC NFYC NR1H4 OSMR OSTF1 PAFAH1B3 PCDHA4 PCNA PDIA2 PGK1 PLD2 POT1 POU2F2 PPM1E PRDX1 PRKCI PRPF40A PSEN1 PSMD11 RAB2A RBM5 RPA2 S100A6 SERPINB9 SIAH1 SIRT1 SLC2A1 SLC2A4 SMN1 SNCA SUMO4 TERF1 TINF2 TK1 TPPP USP25 YWHAE YWHAQ
Entrez ID		5230	2597
HPRD ID		02412	00713
Ensembl ID		ENSG00000102144	ENSG00000111640
Uniprot IDs		B4E1H9 B7Z7A9 P00558	P04406
PDB IDs		2WZB 2WZC 2WZD 2X13 2X14 2X15 2XE6 2XE7 2XE8 2Y3I 2YBE 2ZGV 3C39 3C3A 3C3B 3C3C 4AXX	1U8F 1ZNQ 2FEH 3GPD
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neuroblast Proliferation Positive Regulation Of Neural Precursor Cell Proliferation Regulation Of Neuroblast Proliferation Positive Regulation Of Stem Cell Proliferation Neural Fold Elevation Formation Positive Regulation Of Deoxyribonuclease Activity Peptidyl-cysteine S-trans-nitrosylation Regulation Of Neural Precursor Cell Proliferation Regulation Of Stem Cell Proliferation Elastin Metabolic Process Leading Strand Elongation Cellular Homeostasis Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Chemokine-mediated Signaling Pathway Vascular Endothelial Growth Factor Production Cerebral Cortex Development Brain Development Microtubule-based Process Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Intestinal Epithelial Cell Maturation Head Development Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Peptidyl-cysteine S-nitrosylation Positive Regulation Of NK T Cell Activation Positive Regulation Of MHC Class I Biosynthetic Process Pallium Development Hemoglobin Biosynthetic Process Axon Transport Of Mitochondrion Wound Healing Involved In Inflammatory Response Oxygen Homeostasis Negative Regulation Of Thymocyte Apoptotic Process Central Nervous System Development B-1 B Cell Homeostasis Negative Regulation Of Oxidative Stress-induced Neuron Death Regulation Of Transforming Growth Factor Beta2 Production Telencephalon Development Positive Regulation Of Receptor Biosynthetic Process Lactate Metabolic Process Translesion Synthesis Response To Organic Substance Positive Regulation Of Hormone Biosynthetic Process MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Glycolytic Process Negative Regulation Of Mesenchymal Cell Apoptotic Process Response To Muscle Activity Hemoglobin Metabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress MRNA Transcription	Developmental Process Regulation Of Cell Death Regulation Of Apoptotic Process Apoptotic Process Programmed Cell Death Cell Death Death System Development Response To Stimulus Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Intracellular Transport Regulation Of Cellular Response To Heat Regulation Of Cellular Component Organization Anatomical Structure Development Regulation Of Establishment Of Protein Localization Positive Regulation Of Apoptotic Process Multicellular Organismal Development Response To Abiotic Stimulus Cellular Response To Stimulus Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Localization Regulation Of Protein Localization Regulation Of Cellular Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Organelle Organization Neuron Apoptotic Process Cell Cycle Cellular Response To Stress Regulation Of Catalytic Activity Neuron Death Negative Regulation Of Protein Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Phosphorylation Cellular Response To Heat Negative Regulation Of Transferase Activity Regulation Of Organelle Organization Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Homeostatic Process Positive Regulation Of Intracellular Transport Cell Differentiation Positive Regulation Of Metabolic Process Cellular Component Assembly Positive Regulation Of Signal Transduction Mitotic Cell Cycle Phase Transition
Tagcloud ?		4a act1 apparatus carrying compete differing efficiencies enter entry exponential hsp12 hsp26 idea inert lacz leaders mrnas polysome pyk1 raising rp29 rpl3 saccharomyces starvation stationary thi4 translatabilities translated translational	apart caenorhabditis cloning cyst drive elegans ends flanking frame genetics globodera gluconeogenesis glyceraldehyde glycolysis gonads gpd green leader microinjected nematode nucleotides obligatory parasitic pathogenicity potato rostochiensis sl1 spliced
Tagcloud (Difference) ?		4a act1 apparatus carrying compete differing efficiencies enter entry exponential hsp12 hsp26 idea inert lacz leaders mrnas polysome pyk1 raising rp29 rpl3 saccharomyces starvation stationary thi4 translatabilities translated translational	apart caenorhabditis cloning cyst drive elegans ends flanking frame genetics globodera gluconeogenesis glyceraldehyde glycolysis gonads gpd green leader microinjected nematode nucleotides obligatory parasitic pathogenicity potato rostochiensis sl1 spliced
Tagcloud (Intersection) ?