PGK1 and HSPH1

Number of citations of the paper that reports this interaction (PMID 14733918)
1

Data Source:
HPRD (in vitro)

		PGK1	HSPH1
Gene Name		phosphoglycerate kinase 1	heat shock 105kDa/110kDa protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane Extracellular Vesicular Exosome	Extracellular Region Nucleoplasm Cytoplasm Cytosol Microtubule Extracellular Vesicular Exosome Endocytic Vesicle Lumen
	Molecular Function	Phosphoglycerate Kinase Activity Protein Binding ATP Binding	Protein Binding ATP Binding Alpha-tubulin Binding
	Biological Process	Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Pathogenesis Phosphorylation Epithelial Cell Differentiation Small Molecule Metabolic Process	Receptor-mediated Endocytosis Response To Unfolded Protein Positive Regulation Of MHC Class I Biosynthetic Process Chaperone Mediated Protein Folding Requiring Cofactor Positive Regulation Of NK T Cell Activation
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates	Scavenging by Class F Receptors
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: DISC1 GAPDH HIF1A HSPH1 PCNA SUMO4 YWHAQ	14 interactors: ADD1 CFL1 CHD3 CSNK2A1 CSNK2A2 DYNLRB1 HSPA8 PAFAH1B1 PAFAH1B3 PGK1 STK39 TUBA4A UBA1 VAV2
Entrez ID		5230	10808
HPRD ID		02412	09990
Ensembl ID		ENSG00000102144	ENSG00000120694
Uniprot IDs		B4E1H9 B7Z7A9 P00558	B4DYH1 Q92598
PDB IDs		2WZB 2WZC 2WZD 2X13 2X14 2X15 2XE6 2XE7 2XE8 2Y3I 2YBE 2ZGV 3C39 3C3A 3C3B 3C3C 4AXX
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neuroblast Proliferation Positive Regulation Of Neural Precursor Cell Proliferation Regulation Of Neuroblast Proliferation Positive Regulation Of Stem Cell Proliferation Neural Fold Elevation Formation Positive Regulation Of Deoxyribonuclease Activity Peptidyl-cysteine S-trans-nitrosylation Regulation Of Neural Precursor Cell Proliferation Regulation Of Stem Cell Proliferation Elastin Metabolic Process Leading Strand Elongation Cellular Homeostasis Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Chemokine-mediated Signaling Pathway Vascular Endothelial Growth Factor Production Cerebral Cortex Development Brain Development Microtubule-based Process Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Intestinal Epithelial Cell Maturation Head Development Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Peptidyl-cysteine S-nitrosylation Positive Regulation Of NK T Cell Activation Positive Regulation Of MHC Class I Biosynthetic Process Pallium Development Hemoglobin Biosynthetic Process Axon Transport Of Mitochondrion Wound Healing Involved In Inflammatory Response Oxygen Homeostasis Negative Regulation Of Thymocyte Apoptotic Process Central Nervous System Development B-1 B Cell Homeostasis Negative Regulation Of Oxidative Stress-induced Neuron Death Regulation Of Transforming Growth Factor Beta2 Production Telencephalon Development Positive Regulation Of Receptor Biosynthetic Process Lactate Metabolic Process Translesion Synthesis Response To Organic Substance Positive Regulation Of Hormone Biosynthetic Process MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Glycolytic Process Negative Regulation Of Mesenchymal Cell Apoptotic Process Response To Muscle Activity Hemoglobin Metabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress MRNA Transcription	Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Cell Morphogenesis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Axon Guidance Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Movement Of Cell Or Subcellular Component Neuron Development Cell Cycle Process Chemotaxis Neuron Differentiation Cell Projection Organization Mitotic Cell Cycle Process Locomotion Mitotic Cell Cycle Cell Cycle Nervous System Development Generation Of Neurons Secretion By Cell Platelet Activation Anatomical Structure Morphogenesis Neurogenesis Cell Differentiation Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Cytoskeleton Organization Cell Development Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint 'de Novo' Posttranslational Protein Folding Secretion Regulation Of Mitotic Metaphase/anaphase Transition 'de Novo' Protein Folding Anatomical Structure Development Regulation Of Cellular Component Organization Chaperone-mediated Protein Folding Protein Folding Negative Regulation Of Fibril Organization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Actin Filament Depolymerization Platelet Degranulation Microtubule-based Process Regulation Of Cellular Component Size Negative Regulation Of Cellular Protein Catabolic Process
Tagcloud ?		4a act1 apparatus carrying compete differing efficiencies enter entry exponential hsp12 hsp26 idea inert lacz leaders mrnas polysome pyk1 raising rp29 rpl3 saccharomyces starvation stationary thi4 translatabilities translated translational	accordingly aggressive aggressiveness bcl candidacy clarify concurrently confirming delay favors hodgkin injected interacts lymphoma lymphomas myc namalwa nhl nhls oncoproteins paralleled physically positively silenced stabilization tumorigenicity valuable
Tagcloud (Difference) ?		4a act1 apparatus carrying compete differing efficiencies enter entry exponential hsp12 hsp26 idea inert lacz leaders mrnas polysome pyk1 raising rp29 rpl3 saccharomyces starvation stationary thi4 translatabilities translated translational	accordingly aggressive aggressiveness bcl candidacy clarify concurrently confirming delay favors hodgkin injected interacts lymphoma lymphomas myc namalwa nhl nhls oncoproteins paralleled physically positively silenced stabilization tumorigenicity valuable
Tagcloud (Intersection) ?