ATP5PF and INPP5K

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATP5PF	INPP5K
Description		ATP synthase peripheral stalk subunit F6	inositol polyphosphate-5-phosphatase K
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Proton-transporting ATP Synthase Complex	Ruffle Nucleus Cytoplasm Endoplasmic Reticulum Trans-Golgi Network Cytosol Plasma Membrane Membrane Ruffle Membrane Neuron Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Inositol-polyphosphate 5-phosphatase Activity Vasopressin Receptor Activity Protein Binding Inositol Bisphosphate Phosphatase Activity Hydrolase Activity Phosphatase Activity Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Phosphatidylinositol Trisphosphate Phosphatase Activity Phosphatidylinositol Phosphate 5-phosphatase Activity Lipid Phosphatase Activity Inositol Trisphosphate Phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
	Biological Process	Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Substantia Nigra Development Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	In Utero Embryonic Development Regulation Of Glycogen Biosynthetic Process Lipid Metabolic Process Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process G Protein-coupled Receptor Signaling Pathway Negative Regulation Of D-glucose Transmembrane Transport Actin Cytoskeleton Organization Response To Insulin Cellular Response To Insulin Stimulus Cellular Response To Hormone Stimulus Negative Regulation Of Dephosphorylation Positive Regulation Of Urine Volume Glucose Homeostasis Host-mediated Suppression Of Viral Transcription Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Glycerolipid Metabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol Dephosphorylation Regulation Of Transport Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Calcium Ion Transport Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Negative Regulation Of Protein Targeting To Membrane Ruffle Assembly Cellular Response To Oxygen-containing Compound Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Renal Water Transport
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation Mitochondrial protein degradation	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS			Mean platelet volume ( 27863252)
Interacting Genes		17 interacting genes: ABHD16A BCL2L2 INPP5K KCNK5 MALL MAPK6 MIEF1 MIEF2 MOSPD3 NDRG4 PHOSPHO2 PLP2 PTPN9 REEP6 RPS6KA3 SFT2D2 SIGLEC12	23 interacting genes: ANXA7 ARL6IP1 ATP5PF BDNF CDKN1A CPTP FADS6 FATE1 FBXO7 GOLT1B HMOX2 HSPB1 KRT31 NCOR2 PBX3 PFDN1 SFT2D2 SMN1 TANK TK1 TNFRSF10D TNKS TTR
Entrez ID		522	51763
HPRD ID		04399	08489
Ensembl ID		ENSG00000154723	ENSG00000132376
Uniprot IDs		P18859 Q6IB54 Q6NZ59	B7Z4V9 Q9BT40
PDB IDs		8H9G 8H9K 8H9N 8H9R 8H9S 8H9T 8H9U 8H9V 8KI3
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Localization Regulation Of Protein Targeting To Membrane Positive Regulation Of Mitochondrial Fission Mitochondrial Fusion Positive Regulation Of Protein Targeting To Membrane Regulation Of Mitochondrial Fission
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