ATP5PF and NDRG4

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		ATP5PF	NDRG4
Name		ATP synthase peripheral stalk subunit F6	NDRG family member 4
Structure			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Proton-transporting ATP Synthase Complex	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Basolateral Plasma Membrane Cell Projection Membrane
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism	Molecular_function Protein Binding
	Biological Process	Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Substantia Nigra Development Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Heart Looping Signal Transduction Visual Learning Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Negative Regulation Of Smooth Muscle Cell Migration Cell Differentiation Embryonic Heart Tube Development Vesicle Docking Negative Regulation Of Smooth Muscle Cell Proliferation Cardiac Muscle Cell Proliferation Cell Migration Involved In Heart Development Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Endocytic Recycling
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation Mitochondrial protein degradation	None
GWAS		No GWAS studies recorded	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) Electrocardiographic traits ( 20062063 ) Liver enzyme levels (alanine transaminase) ( 33972514 ) Oily fish consumption ( 32066663 ) Pork consumption ( 32066663 ) QT interval ( 19305408 19305409 22726844 ) Schizophrenia ( 29483656 )
Interacting Genes		17 interacting genes: ABHD16A BCL2L2 INPP5K KCNK5 MALL MAPK6 MIEF1 MIEF2 MOSPD3 NDRG4 PHOSPHO2 PLP2 PTPN9 REEP6 RPS6KA3 SFT2D2 SIGLEC12	37 interacting genes: AGTRAP APLNR ARFIP2 ARL6IP1 ATP5PF BCL2L13 CACFD1 CDR1 CIDEB CMTM5 COQ3 CPLX2 DERL3 DGAT2L6 ERGIC3 LEUTX LIME1 LRRC59 MAL2 MTIF3 PLP2 PRAF2 RABAC1 REEP6 RTN3 SCAMP1 SDR16C5 SFT2D2 SGK1 SIN3A SMPD2 SYNGR1 SYNGR3 SYP THAP4 TMEM208 YIF1A
Entrez ID		522	65009
HPRD ID		04399	14817
Ensembl ID		ENSG00000154723	ENSG00000103034
Uniprot IDs		P18859 Q6IB54 Q6NZ59	A0A0S2Z5L7 A0A0S2Z5R7 B7Z9X4 Q9ULP0
PDB IDs		8H9G 8H9K 8H9N 8H9R 8H9S 8H9T 8H9U 8H9V 8KI3	Not available
GO Terms Enriched among Interactors		Regulation Of Cellular Localization Regulation Of Protein Targeting To Membrane Positive Regulation Of Mitochondrial Fission Mitochondrial Fusion Positive Regulation Of Protein Targeting To Membrane Regulation Of Mitochondrial Fission	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Synaptic Vesicle Vesicle-mediated Transport Endoplasmic Reticulum Tubular Network Formation Cytoplasmic Vesicle Endoplasmic Reticulum Tubular Network Membrane Organization Synaptic Vesicle Membrane Regulation Of Synaptic Vesicle Priming Protein Binding Regulation Of Short-term Neuronal Synaptic Plasticity Endoplasmic Reticulum Organization Synaptic Vesicle Membrane Organization Endoplasmic Reticulum Membrane Organization