ATP5PF and SIGLEC12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATP5PF	SIGLEC12
Description		ATP synthase peripheral stalk subunit F6	sialic acid binding Ig like lectin 12
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Proton-transporting ATP Synthase Complex	Plasma Membrane Membrane
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism	Protein Binding Carbohydrate Binding Sialic Acid Binding
	Biological Process	Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Substantia Nigra Development Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Cell Adhesion
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation Mitochondrial protein degradation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS
Interacting Genes		17 interacting genes: ABHD16A BCL2L2 INPP5K KCNK5 MALL MAPK6 MIEF1 MIEF2 MOSPD3 NDRG4 PHOSPHO2 PLP2 PTPN9 REEP6 RPS6KA3 SFT2D2 SIGLEC12	17 interacting genes: ACSF2 ADIPOQ ATP5PF CDIPT CLEC4G CMAS CTSA DNAJC30 IL1RL1 MGST1 PLPP6 PLPPR2 PTCH1 PTPN11 PTPN6 TMPRSS4 YIPF1
Entrez ID		522	89858
HPRD ID		04399	16195
Ensembl ID		ENSG00000154723	ENSG00000254521
Uniprot IDs		P18859 Q6IB54 Q6NZ59	Q96PQ1
PDB IDs		8H9G 8H9K 8H9N 8H9R 8H9S 8H9T 8H9U 8H9V 8KI3
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Localization Regulation Of Protein Targeting To Membrane Positive Regulation Of Mitochondrial Fission Mitochondrial Fusion Positive Regulation Of Protein Targeting To Membrane Regulation Of Mitochondrial Fission	Regulation Of Neutrophil Activation Phosphate-containing Compound Metabolic Process Dephosphorylation Organophosphate Metabolic Process Negative Regulation Of Neutrophil Activation Non-membrane Spanning Protein Tyrosine Phosphatase Activity Negative Regulation Of Adaptive Immune Response Negative Regulation Of Cell-cell Adhesion Negative Regulation Of T Cell Proliferation Neutrophil Activation Involved In Immune Response Brain Development Phosphatidate Phosphatase Activity Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Leukocyte Proliferation Negative Regulation Of Immune System Process Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Cell Adhesion Platelet Formation Megakaryocyte Development Positive Regulation Of Viral Life Cycle Positive Regulation Of Cholesterol Efflux Regulation Of Lipid Transport Negative Regulation Of T Cell Activation Negative Regulation Of Cytokine Production Regulation Of Lipopolysaccharide-mediated Signaling Pathway Neutrophil Activation Regulation Of Cell Activation Lipid Modification Cellular Response To Lipid Hydroperoxide Negative Regulation Of Cell Population Proliferation Neural Plate Axis Specification Regulation Of Cholesterol Efflux Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Cholesterol Transport Reproductive Structure Development Cytokine-mediated Signaling Pathway Regulation Of T Cell Proliferation Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Cell Activation Negative Regulation Of Lymphocyte Activation Regulation Of Tumor Necrosis Factor Production T Cell Costimulation Regulation Of Cytokine-mediated Signaling Pathway Epididymis Development Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Positive Regulation Of D-glucose Import Positive Regulation Of D-glucose Transmembrane Transport
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