HMOX2 and NKRF

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		HMOX2	NKRF
Gene Name		heme oxygenase (decycling) 2	NFKB repressing factor
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Membrane	Nucleus Nucleolus Endoplasmic Reticulum
	Molecular Function	Heme Oxygenase (decyclizing) Activity Protein Binding Metal Ion Binding	DNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Response To Hypoxia Porphyrin-containing Compound Metabolic Process Heme Oxidation Cellular Iron Ion Homeostasis Heme Catabolic Process Small Molecule Metabolic Process Transmembrane Transport	Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated
Pathways		Iron uptake and transport Metabolism of porphyrins Heme degradation
Drugs		NADH
Diseases
GWAS
Protein-Protein Interactions		32 interactors: A2M APP ATP5B BLOC1S2 CEBPZ COPS6 CSNK2A1 EEF1G EIF3C GIT1 GPRASP1 HAP1 IMMT INPP5K ITFG1 JADE1 KCNMA1 KIAA1377 LRIF1 MED31 NDUFS2 NKRF NR3C1 PLXNB2 RBBP4 SETDB1 SHC1 SKA2 SNX5 SNX7 ZFP28 ZNF746	7 interactors: DHX58 HMOX2 NFKB1 NFKB2 PRKRA REL RELA
Entrez ID		3163	55922
HPRD ID		00783	02341
Ensembl ID		ENSG00000103415	ENSG00000186416
Uniprot IDs		I3L430 P30519	A3F768 A3F769 O15226
PDB IDs		2Q32 2QPP 2RGZ
Enriched GO Terms of Interacting Partners?		Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Axon Cargo Transport Cellular Macromolecule Biosynthetic Process Organelle Organization Macromolecule Biosynthetic Process RNA Metabolic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Cellular Process Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of ERBB Signaling Pathway Regulation Of Mitotic Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle Phase Transition Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cell Cycle Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Receptor Activity Cell Projection Organization Cellular Nitrogen Compound Metabolic Process Anterograde Axon Cargo Transport Microtubule-based Transport Positive Regulation Of Cellular Biosynthetic Process Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Body Fluid Levels Cytoskeleton-dependent Intracellular Transport Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Glucocorticoid Mediated Signaling Pathway Positive Regulation Of Renal Water Transport Regulation Of Cellular Process Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Cellular Response To CAMP Cellular Homeostasis Regulation Of Mitotic Cell Cycle Platelet Activation	NIK/NF-kappaB Signaling Regulation Of Interleukin-12 Biosynthetic Process Positive Regulation Of Type I Interferon Production Regulation Of Type I Interferon Production Positive Regulation Of Cytokine Production Regulation Of Cytokine Production Immune Response Toll-like Receptor 5 Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor 10 Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Interleukin-12 Production TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Innate Immune Response Positive Regulation Of MiRNA Metabolic Process Toll-like Receptor 4 Signaling Pathway Response To Stress Cellular Response To Nicotine Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Cytokine Biosynthetic Process Response To Oxidative Stress Toll-like Receptor Signaling Pathway Inflammatory Response Regulation Of MiRNA Metabolic Process Immune System Process Positive Regulation Of NF-kappaB Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Signal Transduction Negative Regulation Of Gene Expression Membrane Protein Intracellular Domain Proteolysis Defense Response Positive Regulation Of Innate Immune Response Cellular Response To Interleukin-6 Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Cytokine Response To Other Organism Response To Biotic Stimulus Response To Interleukin-6 Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intracellular Signal Transduction Membrane Protein Proteolysis
Tagcloud ?			alveolar concomitant contact downregulates elucidated endogenous fully heated hinder il interference ip kappab loads macrophages mononuclear mtb mycobacterium p65 recruitment repressing repressive repressor robust serves synthesis tb thp understood
Tagcloud (Difference) ?			alveolar concomitant contact downregulates elucidated endogenous fully heated hinder il interference ip kappab loads macrophages mononuclear mtb mycobacterium p65 recruitment repressing repressive repressor robust serves synthesis tb thp understood
Tagcloud (Intersection) ?