SLC15A2 and KRTAP12-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC15A2	KRTAP12-2
Description		solute carrier family 15 member 2	keratin associated protein 12-2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Extracellular Exosome	Cytosol Intermediate Filament
	Molecular Function	Protein Binding Symporter Activity Peptide:proton Symporter Activity Transmembrane Transporter Activity Oligopeptide Transmembrane Transporter Activity Tripeptide Transmembrane Transporter Activity Dipeptide Transmembrane Transporter Activity	Protein Binding
	Biological Process	Immune System Process Oligopeptide Transport Protein Transport Peptide Transport Peptidoglycan Transport Xenobiotic Transport Dipeptide Transport Innate Immune Response Transmembrane Transport Renal Absorption Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Dipeptide Import Across Plasma Membrane Tripeptide Import Across Plasma Membrane Antibacterial Innate Immune Response Transport Across Blood-brain Barrier Proton Transmembrane Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways			Keratinization
Drugs		Ampicillin Cefotaxime Oxacillin Benzylpenicillin
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Estimated glomerular filtration rate ( 30604766 31015462 31152163 31451708) Glomerular filtration rate ( 29403010) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Multiple sclerosis ( 21833088) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		26 interacting genes: ADAM12 ANKS1A AQP1 C11orf87 CHRD ENKD1 KLHL38 KPRP KRT34 KRTAP12-2 KRTAP12-3 KRTAP15-1 KRTAP26-1 KRTAP6-3 LMO4 NHERF4 NTAQ1 OTX1 PDZK1 PITX1 PLSCR4 SMARCC1 TENT5B TLX3 VENTX WWOX	127 interacting genes: ADAM12 ARID5A ATN1 ATP6V1C2 AVPI1 BCL6B BEX2 CATSPER1 CBLL2 CBX2 CCNL1 CCNL2 CFP CHRD CNNM3 CYSRT1 DGCR6 DHRS1 EFEMP2 ETNK2 FAM27E3 FHL3 FOXD4 FOXD4L1 FOXD4L3 GDF15 GPANK1 GPRIN2 GREM1 HOXA1 HOXB9 HSFX1 HSFX2 HYPK INO80B IQUB KRT34 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-4 KRTAP13-2 KRTAP15-1 KRTAP19-2 KRTAP21-2 KRTAP26-1 KRTAP3-2 KRTAP4-2 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1F LCE2A LCE2B LCE4A LCE5A LINC00671 MEOX2 MGAT5B MYOZ1 MYPOP NBPF19 NECTIN2 NOTCH2NLA NPDC1 NR1D2 ODF1 OTX1 PACSIN3 PATZ1 PCSK5 PDE9A PELO PHLDA1 PIH1D2 PLAC8 POLR1C POM121L8P POU4F2 RAD23A RBM39 RBPMS RBX1 RHOXF2 SEMA3B SLC12A4 SLC13A5 SLC15A2 SLC15A3 SPATA3 SPMIP9 SPRED2 SPRY1 SRSF8 TCEA2 TINAGL1 TLE5 TMEM179B TNS2 TRIM42 TRIP13 TSGA10IP TTPA VASN VENTX VGLL3 YIPF3 YY1 ZBTB9 ZDHHC1 ZIM2 ZNF100 ZNF408 ZNF497 ZNF581 ZNF587 ZNF624 ZNF688 ZNF696 ZNF764 ZNF785 ZNHIT1
Entrez ID		6565	353323
HPRD ID		09088	11198
Ensembl ID		ENSG00000163406	ENSG00000221864
Uniprot IDs		Q16348	P59991
PDB IDs		6EZI 7PMY
Enriched GO Terms of Interacting Partners?		Intermediate Filament Brush Border	Intermediate Filament Keratinization Keratin Filament Epidermis Development Protein Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of RNA Metabolic Process Sequence-specific DNA Binding Tissue Development Regulation Of Nucleobase-containing Compound Metabolic Process Peptidoglycan Transport Identical Protein Binding Peptide:proton Symporter Activity Dipeptide Transmembrane Transporter Activity Negative Regulation Of Lens Fiber Cell Differentiation Dipeptide Transmembrane Transport Dipeptide Import Across Plasma Membrane Dipeptide Transport
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